SCHEMBL3629587

SCHEMBL3629587

Cc1ccc(C=CC=O)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 2/20 0.42
POLB P06746 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MAPT P10636 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AMY1A P0DUB6 1/20 0.40
CDK4 P11802 2/20 0.39
CCND1 P24385 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TP53 P04637 1/20 0.37
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14674514 1.00 CYP1A1 (0.43) CYP1A1CYP1B1TDP1LMNAMEN1
SCHEMBL14384897 0.83 ALOX5 (0.50) TDP1LMNAMEN1KMT2AKDM4E
SCHEMBL11323718 0.82 AMY1A (0.47) CYP1A1CYP1B1TDP1LMNAMEN1
SCHEMBL6546420 0.82 AMY1A (0.47) CYP1A1CYP1B1TDP1LMNAMEN1
SCHEMBL7258077 0.80 ALDH1A1 (0.45) LMNAMEN1KMT2AKDM4EPOLB
SCHEMBL7855651 0.80 KDM4E (0.48) TDP1KDM4EMAPTCDK4CCND1
SCHEMBL13348211 0.80 NFE2L2 (0.51) CYP1A1CYP1B1LMNAKDM4EMAPT
SCHEMBL12402952 0.80 GABRA1 (0.45) TDP1LMNAMEN1KMT2AKDM4E
SCHEMBL13763239 0.80 ALDH1A1 (0.45) LMNAMEN1KMT2AKDM4EPOLB
SCHEMBL17326895 0.79 CYP1A1 (0.40) CYP1A1CYP1B1TDP1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565328-A COLORIMETRIC ANALYSIS WITH FLUOROMETRIC READER USING SUITABLE FLUOROPHORE DADE INTERNATIONAL INC. (US) 1996-10-15 US claimed
CN-114053754-B Two-phase deep eutectic solvent for simultaneously separating and extracting multiple active ingredients from waste ginkgo nut exocarp and extraction method thereof 南京林业大学 2023-07-21 CN disclosed
US-11685741-B2 Fluorescent probes UNIVERSITY OF MASSACHUSETTS (US) 2023-06-27 US disclosed
CN-110742913-B Deep eutectic solvent for solubilizing ginkgo leaf extract and preparation method and application thereof 南京林业大学 2022-06-21 CN disclosed
CN-114053754-A Two-phase deep eutectic solvent for simultaneously separating and extracting multiple active ingredients from waste ginkgo nut testa and extraction method thereof 南京林业大学 2022-02-18 CN disclosed
US-20220009940-A1 FLUORESCENT PROBES NATIONAL SCIENCE FOUNDATION 2022-01-13 US disclosed
CN-107789376-B Two-phase deep eutectic solvent for extracting active ingredients of ginkgo leaves and preparation method and extraction method thereof 南京林业大学 2021-05-18 CN disclosed
CN-107484549-B Method for solid-state fermentation of ginkgo leaves by eurotium cristatum and application of ginkgo leaves 南京林业大学 2020-09-25 CN disclosed
CN-111493194-A Coating for edible cores, systems, methods and coated products thereof 洲际大品牌有限责任公司 2020-08-07 CN disclosed
CN-110742913-A Deep eutectic solvent for solubilizing ginkgo leaf extract and preparation method and application thereof 南京林业大学 2020-02-04 CN disclosed
EP-1745278-A4 COLORIMETRIC AND FLUOROMETRIC DETERMINATION OF HOMOCYSTEINE AND CYSTEINE UNIV LOUISIANA STATE (US) 2008-05-28 EP disclosed
EP-1745278-A2 COLORIMETRIC AND FLUOROMETRIC DETERMINATION OF HOMOCYSTEINE AND CYSTEINE THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2007-01-24 EP disclosed
WO-2005110109-A2 COLORIMETRIC AND FLUOROMETRIC DETERMINATION OF HOMOCYSTEINE AND CYSTEINE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2005-11-24 WO disclosed
EP-0925369-B1 UNIVERSAL TEST SYSTEMS AND METHODS OF USE THEREOF FOR IDENTIFYING MULTIPLE FAMILIES OF MICROORGANISMS DADE MICROSAN INC (US) 2003-05-28 EP disclosed
EP-1293575-A2 Universal test system and methods of use thereof for indentifying multiple families of microorganisms Dade Microsan Inc. (US) 2003-03-19 EP disclosed
EP-0925369-A1 UNIVERSAL TEST SYSTEMS AND METHODS OF USE THEREOF FOR IDENTIFYING MULTIPLE FAMILIES OF MICROORGANISMS Dade Microsan Inc. (US) 1999-06-30 EP disclosed
US-5888760-A COMBINATION OF NON-REDUNDANT TESTS IN REACTION CHAMBERS CONTAINING SUBSTRATES FOR ENZYMATIC CLASSIFICATION BY DETECTION OF FLUORESCENT OR COLORIMETRIC PRODUCTS FORMED DADE MICROSCAN INC. (US) 1999-03-30 US disclosed
WO-1998045469-A1 UNIVERSAL TEST SYSTEMS AND METHODS OF USE THEREOF FOR IDENTIFYING MULTIPLE FAMILIES OF MICROORGANISMS DADE MICROSCAN INC. (US) 1998-10-15 WO disclosed
EP-0254578-A1 Antibiotic intermediates ELI LILLY AND COMPANY (US) 1988-01-27 EP disclosed
US-3716336-A METHOD FOR DETERMINING PROCAINAMIDE LEVELS IN BLOOD OR URINE SQUIBB & SONS INC 1973-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009940-A1 FLUORESCENT PROBES FECH, CHERP, SLC40A1 CYP1A1 3647/4885CYP1B1 2753/4885TDP1 1690/4885
US-11685741-B2 Fluorescent probes FECH, CHERP, SLC40A1 CYP1A1 3647/4885CYP1B1 2753/4885TDP1 1690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.