Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 7/20 | 0.36 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663846 | 0.79 | SIGMAR1 (0.47) | — | |
| SCHEMBL3627515 | 0.76 | KDM4E (0.37) | USP2ALDH1A1 | |
| SCHEMBL3320791 | 0.74 | HTR1A (0.43) | HRH3HTR3AHTR1AALDH1A1CYP1A2 | |
| SCHEMBL3632725 | 0.74 | ACHE (0.44) | HRH3 | |
| SCHEMBL3634835 | 0.74 | L3MBTL1 (0.46) | ALDH1A1 | |
| SCHEMBL3633470 | 0.72 | GBA1 (0.45) | — | |
| SCHEMBL3632360 | 0.72 | FPR2 (0.43) | HRH3 | |
| SCHEMBL3632511 | 0.71 | KDM2B (0.42) | HTR1A | |
| SCHEMBL3633458 | 0.70 | HRH3 (0.39) | HRH3HTR3ASORDSETDB1NPC1 | |
| SCHEMBL3633554 | 0.70 | KDM2B (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155748-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2010-02-24 | — | — | EP | claimed |
| WO-2008144268-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-27 | — | — | WO | claimed |