Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GCK | P35557 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960903 | 0.85 | ABL1 (0.61) | FADS1RECQLALDH1A1KDM4ENPC1 | |
| SCHEMBL1095186 | 0.85 | ALDH1A1 (0.70) | FADS1RECQLGCKALDH1A1KDM4E | |
| SCHEMBL140037 | 0.83 | FADS1 (0.59) | FADS1RECQLGCKALDH1A1KDM4E | |
| SCHEMBL8208503 | 0.80 | FADS1 (0.56) | FADS1RECQLGCKALDH1A1KDM4E | |
| SCHEMBL6587131 | 0.80 | FADS1 (0.74) | FADS1GCKALDH1A1HDAC1 | |
| SCHEMBL14215697 | 0.80 | MAPT (0.59) | FADS1RECQLALDH1A1KDM4ENPC1 | |
| SCHEMBL9540049 | 0.79 | RECQL (0.79) | FADS1RECQLGCKALDH1A1KDM4E | |
| SCHEMBL11689255 | 0.79 | NOS2 (0.63) | FADS1RECQLGCKALDH1A1ABL1 | |
| SCHEMBL13761455 | 0.79 | FADS1 (0.55) | FADS1RECQLGCKALDH1A1KDM4E | |
| SCHEMBL4339605 | 0.79 | FADS1 (0.55) | FADS1RECQLGCKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| EP-2170822-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | Luxembourg Bio Technologies Ltd. (IL) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009138985-A2 | COUPLING AGENTS FOR THE SYNTHESIS OF POLYPEPTIDES AND POLYNUCLEOTIDES | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009138985-A2 | COUPLING AGENTS FOR THE SYNTHESIS OF POLYPEPTIDES AND POLYNUCLEOTIDES | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2009-11-19 | — | — | WO | disclosed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | disclosed |
| US-6429311-B2 | CHEMICAL INTERMEDIATE FOR HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES, ANTIPYRETICS AND ANTIDEPRESSANTS | SEPRACOR INC. | 2002-08-06 | — | — | US | disclosed |
| US-20010018518-A1 | Compositions containing N-amino- and N-hydroxy-quinazolinones and methods for preparing libraries thereof | GAO YUN (US) | 2001-08-30 | — | — | US | disclosed |
| US-6184377-B1 | ANTIPYRETIC, HYPOTENSIVE, ANTIBACTERIAL, ANTIFUNGAL OR CENTRAL NERVOUS SYSTEM (CNS) ACTIVITY, AS WELL AS THE ABILITY TO INHIBIT ENZYMES | SEPRACOR INC. | 2001-02-06 | — | — | US | disclosed |
| EP-0174412-B1 | STABILISATION OF THERMOPLASTICS CONTAINING CHLORINE WITH ORGANIC COMPOUNDS CONTAINING NITROGEN | CIBA-GEIGY AG (CH) | 1988-10-26 | — | — | EP | disclosed |
| US-4642322-A | Stabilization of chlorine-containing thermoplastics with nitrogen-containing organic compounds | CIBA-GEIGY CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |
| WO-1986001812-A1 | STABILIZER OF CHLORINE-CONTAINING THERMOPLASTS WITH NITROGEN-CONTAINING ORGANIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1986-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | PHAX, GIPR, IAPP | FADS1 4228/4885RECQL 800/4885GCK 1244/4885 |
| US-20010018518-A1 | Compositions containing N-amino- and N-hydroxy-quinazolinones and methods for preparing libraries thereof | NQO2, ASNS, AAAS | FADS1 395/4885RECQL 476/4885GCK 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.