Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640371 | 0.87 | ERN1 (0.44) | PTGS1PTGS2ALOX5ERN1NQO2 | |
| SCHEMBL3724309 | 0.79 | MEN1 (0.36) | PTGS1PTGS2ALOX5HSD17B10ERN1 | |
| SCHEMBL8466904 | 0.75 | ALOX5 (0.50) | AMY1AHSPA5CYP2C9CYP2C19HIF1A | |
| SCHEMBL8466901 | 0.75 | ALOX5 (0.50) | AMY1AHSPA5CYP2C9CYP2C19HIF1A | |
| SCHEMBL3668136 | 0.74 | KCNMA1 (0.44) | HSD17B10 | |
| SCHEMBL3634452 | 0.73 | HKDC1 (0.40) | PTGS1PTGS2ALOX5HSD17B10NQO2 | |
| SCHEMBL18789522 | 0.72 | ALOX5 (0.41) | SMN1; SMN2PTGS1PTGS2ALOX5 | |
| SCHEMBL4533603 | 0.72 | AMY1A (0.45) | AMY1AHSPA5CYP2C9CYP2C19HIF1A | |
| SCHEMBL3727266 | 0.70 | HKDC1 (0.37) | CYP2C9PTGS1PTGS2ALOX5HSD17B10 | |
| SCHEMBL9416952 | 0.70 | LMNA (0.40) | SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |