Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804735 | 0.95 | HTR6 (0.44) | HTR6CHRNB4CHRNA3 | |
| SCHEMBL2606119 | 0.83 | ADRA2A (0.53) | ADRA2AHTR6 | |
| Ammonia Solution, Strong SCHEMBL29771408 | 0.82 | HTR1D (0.49) | HTR6CHRNB4CHRNA3 | |
| Ammonia Solution, Strong SCHEMBL3645001 | 0.81 | ADRA2A (0.51) | ADRA2AHTR6 | |
| SCHEMBL25645586 | 0.81 | ADRA2A (0.51) | ADRA2AHTR6 | |
| SCHEMBL11470450 | 0.81 | ADRA2A (0.51) | ADRA2AHTR6 | |
| SCHEMBL4278447 | 0.80 | CHRNB2 (0.49) | ADRA2AHTR6CHRM1 | |
| SCHEMBL11474181 | 0.79 | DRD2 (0.48) | ADRA2ACYP1A2HTR6 | |
| SCHEMBL11473707 | 0.79 | ALDH1A1 (0.49) | ADRA2ACYP1A2HTR6 | |
| SCHEMBL11486228 | 0.79 | CHRNB2 (0.48) | ADRA2ACYP1A2HTR6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |