Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
| ▸ | HTR2C | P28335 | 3/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.63 |
| ▸ | HRH1 | P35367 | 3/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CCKBR | P32239 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545461 | 0.88 | HTR1A (0.76) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Methyl Alcohol SCHEMBL718327 | 0.86 | HTR1A (0.76) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Methyl Alcohol SCHEMBL3645347 | 0.85 | DRD2 (0.61) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL7356255 | 0.85 | DRD2 (0.77) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Methyl Alcohol SCHEMBL718326 | 0.84 | DRD2 (0.69) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL7963611 | 0.84 | HTR6 (0.74) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL8716361 | 0.83 | HTR1A (0.68) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Methyl Alcohol SCHEMBL142049 | 0.83 | ABCB11 (0.66) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL8561243 | 0.83 | DRD2 (0.73) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL1545822 | 0.82 | HTR1A (0.72) | DRD2HTR1AHTR2AHTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198049-A1 | ANTIPSYCHOTIC TREATMENT BASED ON SNP GENOTYPE | Vanda Pharmaceuticals Inc. (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009036056-A1 | ANTIPSYCHOTIC TREATMENT BASED ON SNP GENOTYPE | VANDA PHARMACEUTICALS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |