SCHEMBL3650243

SCHEMBL3650243

CCCCN(CCCC)NCCO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
S1PR2 O95136 5/20 0.33
S1PR4 O95977 5/20 0.33
S1PR1 P21453 5/20 0.33
S1PR3 Q99500 5/20 0.33
SLC29A1 Q99808 2/20 0.33
ALDH2 P05091 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29105879 0.86 SLC29A1 (0.39) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL28360253 0.82 LMNA (0.42) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL1796804 0.81 TSHR (0.41) ALDH1A1LMNATSHRMMP1MMP2
SCHEMBL181643 0.81 TSHR (0.36) ALDH1A1LMNATSHRMMP1MMP2
SCHEMBL578736 0.81 TSHR (0.41) ALDH1A1LMNATSHRMMP1MMP2
SCHEMBL5699101 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL28841678 0.79 LMNA (0.44) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL28841679 0.79 LMNA (0.44) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL28844793 0.79 TSHR (0.48) ALDH1A1TSHRS1PR2S1PR4S1PR1
SCHEMBL3104555 0.78 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10799610-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2020-10-13 US disclosed
US-10413632-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2019-09-17 US disclosed
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2018-09-20 US disclosed
US-9993576-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2018-06-12 US disclosed
EP-2192886-B1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECH INC (US) 2017-12-20 EP disclosed
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2017-11-23 US disclosed
US-9757493-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2017-09-12 US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 US disclosed
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME TUTOGEN MEDICAL, INC. 2016-09-01 US disclosed
US-9358319-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2016-06-07 US disclosed
EP-2877540-B1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2016-06-01 EP disclosed
US-20150175813-A1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2015-06-25 US disclosed
EP-2877540-A2 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M Innovative Properties Company (US) 2015-06-03 EP disclosed
US-20140357754-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2014-12-04 US disclosed
US-8815973-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2014-08-26 US disclosed
WO-2014018266-A2 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-01-30 WO disclosed
EP-2192886-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME Pioneer Surgical Technology, Inc. (US) 2010-06-09 EP disclosed
US-20090270527-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME ANGSTROM MEDICA (US) 2009-10-29 US disclosed
WO-2009029734-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECHNOLOGY, INC. (US) 2009-03-05 WO disclosed
US-4332733-A CATALYTIC ISOMERIZATION OF DIELS-ALDER MALEIC ANHYDRIDE PRODUCTS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT ALDH1A1 844/4885SMN1; SMN2 4051/4885LMNA 4535/4885
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT ALDH1A1 844/4885SMN1; SMN2 4051/4885LMNA 4535/4885
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT ALDH1A1 844/4885SMN1; SMN2 4051/4885LMNA 4535/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 ALDH1A1 2255/4885SMN1; SMN2 4314/4885LMNA 3764/4885
US-10799610-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT ALDH1A1 844/4885SMN1; SMN2 4051/4885LMNA 4535/4885
US-10413632-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT ALDH1A1 844/4885SMN1; SMN2 4051/4885LMNA 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.