Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365334 | 0.83 | L3MBTL1 (0.47) | L3MBTL1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL366172 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL365335 | 0.72 | CNR2 (0.47) | L3MBTL1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL367332 | 0.72 | HPGD (0.50) | L3MBTL1HPGDKMT2ARAB9AALDH1A1 | |
| SCHEMBL366309 | 0.71 | KDM4E (0.55) | L3MBTL1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL365228 | 0.71 | HPGD (0.47) | HPGDKMT2AMEN1RAB9AKDM4E | |
| SCHEMBL4206984 | 0.69 | L3MBTL1 (0.70) | L3MBTL1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL7422569 | 0.68 | HPGD (0.74) | L3MBTL1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL366113 | 0.67 | EPHX1 (0.49) | L3MBTL1KMT2AMEN1RAB9AKDM4E | |
| SCHEMBL364926 | 0.67 | MAPT (0.49) | L3MBTL1HPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |