Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366481 | 0.92 | ACHE (0.39) | MRGPRX4CYP2D6LTB4RLTB4R2ACHE | |
| SCHEMBL365169 | 0.92 | ACHE (0.41) | CYP2D6LTB4RLTB4R2ACHE | |
| SCHEMBL365769 | 0.91 | LTB4R (0.39) | MRGPRX4LTB4RLTB4R2TP53PKM | |
| SCHEMBL366618 | 0.86 | MEN1 (0.37) | MRGPRX4CYP2D6LTB4RLTB4R2ACHE | |
| SCHEMBL366851 | 0.84 | ALDH1A1 (0.38) | LTB4RLTB4R2TP53 | |
| SCHEMBL365925 | 0.84 | ACHE (0.42) | CYP2D6ACHE | |
| SCHEMBL365189 | 0.84 | ACHE (0.37) | LTB4RLTB4R2ACHESMN1; SMN2ALKBH1 | |
| SCHEMBL365837 | 0.83 | CNR2 (0.37) | LTB4RLTB4R2SMN1; SMN2 | |
| SCHEMBL367734 | 0.80 | ATM (0.40) | PKM | |
| SCHEMBL366751 | 0.80 | PPARG (0.33) | ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |