Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366851 | 0.90 | ALDH1A1 (0.38) | MAPTS1PR3CNR2ALDH1A1KDM4E | |
| SCHEMBL365189 | 0.88 | ACHE (0.37) | S1PR3CNR2ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL365114 | 0.87 | ALDH1A1 (0.34) | PPARGPPARAMAPTKLKB1CNR2 | |
| SCHEMBL365169 | 0.87 | ACHE (0.41) | — | |
| SCHEMBL366900 | 0.84 | S1PR3 (0.39) | S1PR3CNR2ITGB1ITGA4 | |
| SCHEMBL365769 | 0.83 | LTB4R (0.39) | MAPTS1PR3CNR2ITGB1ITGA4 | |
| SCHEMBL366374 | 0.83 | ALDH1A1 (0.38) | MAPTCNR2ALDH1A1 | |
| SCHEMBL366612 | 0.81 | ACHE (0.38) | S1PR3CYP11B1CYP11B2 | |
| SCHEMBL366750 | 0.81 | PPARG (0.33) | PPARGPPARAMAPTCNR2ALDH1A1 | |
| SCHEMBL365593 | 0.80 | MRGPRX4 (0.39) | ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |