Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365837 | 0.92 | CNR2 (0.37) | LTB4RLTB4R2ALOX5CNR2LMNA | |
| SCHEMBL366851 | 0.91 | ALDH1A1 (0.38) | LTB4RLTB4R2CNR2TP53ALDH1A1 | |
| SCHEMBL365593 | 0.91 | MRGPRX4 (0.39) | LTB4RLTB4R2SMN1; SMN2TP53PKM | |
| SCHEMBL365986 | 0.86 | KMT2A (0.38) | LTB4RLTB4R2ALOX5CNR2LMNA | |
| SCHEMBL365169 | 0.84 | ACHE (0.41) | LTB4RLTB4R2 | |
| SCHEMBL366481 | 0.83 | ACHE (0.39) | LTB4RLTB4R2SMN1; SMN2TP53MRGPRX4 | |
| SCHEMBL366374 | 0.83 | ALDH1A1 (0.38) | CNR2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL365189 | 0.83 | ACHE (0.37) | LTB4RLTB4R2CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL366751 | 0.83 | PPARG (0.33) | CNR2ALDH1A1MAPTITGB1ITGA4 | |
| SCHEMBL367734 | 0.82 | ATM (0.40) | LMNAPKMALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |