Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365915 | 0.93 | S1PR3 (0.37) | S1PR3PLA2G4ANPC1RAB9APABPC1 | |
| SCHEMBL365189 | 0.91 | ACHE (0.37) | S1PR3ACHECNR2 | |
| SCHEMBL366851 | 0.90 | ALDH1A1 (0.38) | S1PR3PLA2G4ACNR2 | |
| SCHEMBL366612 | 0.84 | ACHE (0.38) | S1PR3ACHE | |
| SCHEMBL366751 | 0.84 | PPARG (0.33) | S1PR3ITGB1ITGA4CNR2 | |
| SCHEMBL365169 | 0.83 | ACHE (0.41) | ACHE | |
| SCHEMBL365006 | 0.83 | LTB4R (0.35) | S1PR3NPC1RAB9AACHE | |
| SCHEMBL366374 | 0.82 | ALDH1A1 (0.38) | PLA2G4AACHECNR2 | |
| SCHEMBL365769 | 0.81 | LTB4R (0.39) | S1PR3ITGB1ITGA4PKMCNR2 | |
| SCHEMBL366899 | 0.80 | PLA2G4A (0.36) | S1PR3PLA2G4ANPC1RAB9APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |