Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977615 | 0.90 | ALOX5 (0.39) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL975805 | 0.90 | CACNA2D1 (0.38) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL3408675 | 0.88 | DRD2 (0.40) | ALOX5EPHX2DRD2DRD3F2 | |
| Hydrochloric Acid SCHEMBL6519318 | 0.87 | DRD2 (0.39) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL3406225 | 0.86 | SCN9A (0.41) | ALOX5EPHX2DRD2DRD3MEN1 | |
| SCHEMBL979308 | 0.86 | CACNA2D1 (0.41) | DRD2DRD3F2CTSDBACE1 | |
| SCHEMBL3405538 | 0.85 | CTSD (0.39) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL3661726 | 0.85 | CCR2 (0.39) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL3661019 | 0.85 | MEN1 (0.38) | ALOX5EPHX2DRD2DRD3F2 | |
| SCHEMBL977202 | 0.84 | CCR2 (0.39) | CACNA2D1CACNA1BCACNB1CACNA1CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234966-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Sanofi-Aventis (FR) | 2010-10-06 | — | — | EP | claimed |
| WO-2009106708-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | claimed |