Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009625 | 0.93 | TDP1 (0.49) | TDP1ELANEALDH1A1HTR1ASLC6A2 | |
| SCHEMBL8467578 | 0.86 | KMT2A (0.63) | TDP1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL22061929 | 0.86 | KMT2A (0.45) | TDP1ELANEALDH1A1HTR1ASLC6A2 | |
| SCHEMBL29716346 | 0.86 | KMT2A (0.45) | TDP1ELANEALDH1A1HTR1ASLC6A2 | |
| SCHEMBL9910945 | 0.83 | RAB9A (0.56) | ALDH1A1KMT2AMEN1HTTHPGD | |
| SCHEMBL13680418 | 0.83 | KMT2A (0.47) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL2460533 | 0.83 | KMT2A (0.56) | TDP1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8323440 | 0.81 | LTA4H (0.53) | TDP1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL29876758 | 0.81 | LTA4H (0.53) | TDP1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5256557 | 0.80 | KMT2A (0.39) | TDP1ELANEALDH1A1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166601-A1 | NLRX1 LIGANDS | LANDOS BIOPHARMA, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| US-20230337672-A1 | METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230337672-A1 | METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230232827-A1 | METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-27 | — | — | US | disclosed |
| US-20230232827-A1 | METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-27 | — | — | US | disclosed |
| EP-4212513-A1 | 1,3,5-TRIS(6-METHYLPYRIDIN-2-YLOXY)BENZENE DERIVATIVES AND RELATED COMPOUNDS AS NLRX1 LIGANDS FOR TREATING INFLAMMATORY DISEASES | LANDOS BIOPHARMA, INC. (US) | 2023-07-19 | — | — | EP | disclosed |
| US-11680045-B2 | NLRX1 ligands | LANDOS BIOPHARMA, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-3793979-B1 | 1,3,5-TRIS(6-METHYLPYRIDIN-2-YLOXY)BENZENE DERIVATIVES AND RELATED COMPOUNDS AS NLRX1 LIGANDS FOR TREATING INFLAMMATORY DISEASES | LANDOS BIOPHARMA INC (US) | 2022-12-14 | — | — | EP | disclosed |
| CN-112384501-B | 1,3, 5-tris (6-methylpyridin-2-yloxy) benzene derivatives and related compounds as NLRX1ligands for the treatment of inflammatory diseases | 朗多生物制药股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20070142351-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142351-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-7173031-B2 | Pyrrolotriazine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
| US-7164024-B2 | Muscarinic acetylcholine receptor antagonist; Parkinson's disease; dystonia; analgesics; irritable bowel syndrome | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-4776880-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4731107-A | Certain 6-diphenoxymethyl-2-pyridinyl-oxy-propanoates having herbicidal properties | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| US-4692183-A | BROADLEAF GRASSES | THE DOW CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4685953-A | PREEMERGENCE AND POST EMERGENCE HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-08-11 | — | — | US | disclosed |
| US-4661144-A | Certain 6-aminomethyl or monoalkylamino or dialkylamino or heterocyclicamino-2-diphenoxymethyl pyridines having herbicidal activity | THE DOW CHEMICAL COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4606757-A | Diphenoxymethylpyridines having herbicidal properties | THE DOW CHEMICAL COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680045-B2 | NLRX1 ligands | NLRP1, NLRP3, NOD1 | TDP1 2746/4885ELANE 1381/4885ALDH1A1 4423/4885 |
| US-20070142351-A1 | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands | DRD3, DRD2, DRD1 | TDP1 1443/4885ELANE 3681/4885ALDH1A1 1575/4885 |
| US-20240166601-A1 | NLRX1 LIGANDS | NLRP1, NLRP3, NOD1 | TDP1 2746/4885ELANE 1381/4885ALDH1A1 4423/4885 |
| US-20230337672-A1 | METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE | CYC1, SQOR, MT-CO1 | TDP1 4125/4885ELANE 4665/4885ALDH1A1 4422/4885 |
| US-20230232827-A1 | METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES | CYC1, SQOR, MT-CO3 | TDP1 4148/4885ELANE 4681/4885ALDH1A1 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.