Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GRK2 | P25098 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662136 | 0.96 | POLB (0.44) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| SCHEMBL18140724 | 0.96 | POLB (0.44) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| SCHEMBL5536678 | 0.96 | POLB (0.44) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| SCHEMBL18140942 | 0.96 | POLB (0.44) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| SCHEMBL9519688 | 0.88 | POLB (0.46) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| Potassium Ion SCHEMBL5458695 | 0.84 | POLB (0.34) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| SCHEMBL19597 | 0.81 | TGFBR1 (0.35) | POLBGRK2L3MBTL1APAF1DNMT1 | |
| Ammonia Solution, Strong SCHEMBL7211934 | 0.80 | TGFBR1 (0.34) | TGFBR1 | |
| SCHEMBL22158003 | 0.80 | TGFBR1 (0.34) | TGFBR1 | |
| SCHEMBL26106014 | 0.80 | TGFBR1 (0.34) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2025-01-30 | — | — | US | disclosed |
| US-11338562-B2 | Antifogging laminate | MITSUI CHEMICALS, INC. (JP) | 2022-05-24 | — | — | US | disclosed |
| US-20210284862-A1 | Antireflective Laminate | MITSUI CHEMICALS, INC. (JP) | 2021-09-16 | — | — | US | disclosed |
| US-20190202184-A1 | ANTIFOGGING LAMINATE | MITSUI CHEMICALS, INC. (JP) | 2019-07-04 | — | — | US | disclosed |
| EP-3176216-B1 | HYDROPHILIC MATERIAL COMPRISING SULFONATE COPOLYMER AND AMINO RESIN | MITSUI CHEMICALS INC (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9976050-B2 | Hydrophilic materials including sulfonate copolymer and amino resin | MITSUI CHEMICALS, INC. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20180036995-A1 | HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-3270192-A1 | HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF | Mitsui Chemicals, Inc. (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-20170210937-A1 | HYDROPHILIC MATERIALS INCLUDING SULFONATE COPOLYMER AND AMINO RESIN | MITSUI CHEMICALS, INC. (JP) | 2017-07-27 | — | — | US | disclosed |
| EP-3176216-A1 | HYDROPHILIC MATERIAL COMPRISING SULFONATE COPOLYMER AND AMINO RESIN | Mitsui Chemicals, Inc. (JP) | 2017-06-07 | — | — | EP | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-20150126682-A1 | HYDROPHILIC MODIFIED ACRYLIC RESIN FILM | MITSUI CHEMICALS, INC. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2860215-A1 | MODIFIED HYDROPHILIC ACRYLIC RESIN FILM | Mitsui Chemicals, Inc. (JP) | 2015-04-15 | — | — | EP | disclosed |
| EP-1781717-B1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2215134-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | Henkel AG & Co. KGaA (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009071451-A2 | REDUCTION OF THE FORMATION OF BIOFILM BY MEANS OF MULTIFUNCTIONAL COPOLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-06-11 | — | — | WO | disclosed |
| EP-1781717-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006005358-A1 | COPOLYMER-CONTAINING CLEANING COMPOSITIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032398-A1 | HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | PCNA, ADSL, APH1B | POLB 216/4885GRK2 4203/4885L3MBTL1 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.