SCHEMBL3662136

SCHEMBL3662136

C=C(C)C(=O)NC(C)(C)CS(=O)(=O)[O-].[Na+]

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
GRK2 P25098 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
APAF1 O14727 1/20 0.44
DNMT1 P26358 1/20 0.44
PTPN7 P35236 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PPP1CA P62136 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
PTPN22 Q9Y2R2 1/20 0.44
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.42
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL3661338 0.96 POLB (0.44) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL5536678 0.96 POLB (0.44) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL18140942 0.96 POLB (0.44) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL18140724 0.96 POLB (0.44) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL9519688 0.88 POLB (0.46) POLBGRK2L3MBTL1APAF1DNMT1
Potassium Ion SCHEMBL5458695 0.84 POLB (0.34) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL19597 0.81 TGFBR1 (0.35) POLBGRK2L3MBTL1APAF1DNMT1
SCHEMBL28331514 0.81 POLB (0.49) POLBGRK2L3MBTL1APAF1DNMT1
Ammonia Solution, Strong SCHEMBL7211934 0.80 TGFBR1 (0.34) TGFBR1
SCHEMBL22158003 0.80 TGFBR1 (0.34) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250229117-A1 FIREFIGHTING COMPOSITION WITH QUATERNARY FUNCTIONAL COPOLYMER TYCO FIRE PRODUCTS LP (US) 2025-07-17 US claimed
WO-2023144705-A1 FIREFIGHTING COMPOSITION WITH QUATERNARY FUNCTIONAL COPOLYMER TYCO FIRE PRODUCTS LP (US) 2023-08-03 WO claimed
CN-115120749-A Preparation method of radiotherapy microspheres and radiotherapy microspheres 上海玮沐医疗科技有限公司 2022-09-30 CN claimed
US-6100355-A POLYMERIZATION IN THE PRESENCE OF A RADICAL INITIATOR SOLUBLE IN THE MONOMER AND OF A POLYMERIC SUSPENDING AGENT SELECTED FROM SULFONATE CONTAINING ACRYLIC HOMOPOLYMERS ATOHAAS HOLDINGS C.V. (NL) 2000-08-08 US claimed
EP-0774471-B1 Process in suspension for preparing acrylic polymers ATOCHEM ELF SA (FR) 1999-06-23 EP claimed
EP-0683182-B1 Process for preparing acrylic polymers ATOCHEM ELF ITALIA (IT) 1998-11-25 EP claimed
EP-0774471-A1 Process in suspension for preparing acrylic polymers ATOHAAS HOLDING C.V. (NL) 1997-05-21 EP claimed
EP-0558612-B1 POLYMER BLENDS FOR AQUEOUS DISPERSIONS HAVING IMPROVED FREEZE-THAW STABILITY EASTMAN CHEM CO (US) 1996-01-10 EP claimed
EP-0263647-B1 PVA gel SHINETSU CHEMICAL CO (JP) 1994-01-05 EP claimed
US-5268412-A Sulfonate group containing poly(amide)esters EASTMAN KODAK COMPANY (US) 1993-12-07 US claimed
EP-0263647-A2 PVA gel Shin-Etsu Chemical Co., Ltd. (JP) 1988-04-13 EP claimed
US-20250229117-A1 FIREFIGHTING COMPOSITION WITH QUATERNARY FUNCTIONAL COPOLYMER TYCO FIRE PRODUCTS LP (US) 2025-07-17 US disclosed
WO-2025121351-A1 FLUOROELASTOMER PRODUCTION METHOD, COMPOSITION, SOLID COMPOSITION, AND CROSSLINKED RUBBER ARTICLE AGC株式会社 2025-06-12 WO disclosed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
WO-2023144705-A1 FIREFIGHTING COMPOSITION WITH QUATERNARY FUNCTIONAL COPOLYMER TYCO FIRE PRODUCTS LP (US) 2023-08-03 WO disclosed
EP-0227358-A2 Housing pack for photographic processing solution KONICA CORPORATION (JP) 1987-07-01 EP disclosed
EP-0201186-A1 Method of treating photographic waste solutions and automatic photograph processor KONICA CORPORATION (JP) 1986-11-12 EP disclosed
US-4480025-A Water reservoir layers in bleach-fix sheets EASTMAN KODAK COMPANY (US) 1984-10-30 US disclosed
EP-0117165-A2 Bleach-fix sheet EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-08-29 EP disclosed
US-4197127-A STABLE FLEXIVLE COATINGS EASTMAN KODAK COMPANY (US) 1980-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B POLB 216/4885GRK2 4203/4885L3MBTL1 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.