Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520668 | 0.74 | HDAC1 (0.34) | PARP1 | |
| SCHEMBL3626705 | 0.72 | NOTUM (0.37) | — | |
| SCHEMBL15090773 | 0.69 | SCN9A (0.46) | PARP1 | |
| SCHEMBL2887289 | 0.66 | — | — | |
| SCHEMBL15048583 | 0.66 | ALKBH2 (0.46) | — | |
| SCHEMBL27853985 | 0.66 | NPC1 (0.46) | PARP1 | |
| SCHEMBL15520768 | 0.65 | LMNA (0.40) | — | |
| SCHEMBL15520701 | 0.64 | L3MBTL1 (0.50) | PARP1 | |
| SCHEMBL16612728 | 0.62 | NR3C2 (0.43) | PARP1 | |
| SCHEMBL15520585 | 0.62 | CACNA1G (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | claimed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | claimed |
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | disclosed |