Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705904 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL34 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5068661 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL31313 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11432043 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29991938 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| P-Xylene SCHEMBL8660591 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL1160667 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1345322 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL4069335 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399197-A1 | Glycol Ether Ester Compounds Useful In Lubricating Oil Compositions And Methods Of Making Same | EXXONMOBIL RES & ENG CO (US) | 2020-12-24 | — | — | US | claimed |
| US-10738259-B2 | Naphthalene-1,8-dicarboxylate ester compounds and lubricating oil base stocks and processes for making same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-08-11 | — | — | US | claimed |
| EP-3676240-A1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | ExxonMobil Chemical Patents Inc. (US) | 2020-07-08 | — | — | EP | claimed |
| US-10662388-B2 | Ester compounds, lubricating oil compositions containing same and processes for making same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-05-26 | — | — | US | claimed |
| WO-2019045810-A1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-03-07 | — | — | WO | claimed |
| US-20190048280-A1 | Naphthalene-1,8-Dicarboxylate Ester Compounds and Lubricating Oil Base Stocks and Processes for Making Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-02-14 | — | — | US | claimed |
| US-20180282257-A1 | Aromatic Monoester Compositions and Processes for Preparing Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-10-04 | — | — | US | claimed |
| EP-0068080-B1 | LIQUID PHASE SYNTHESIS OF HEXAFLUOROISOBUTYLENE | ALLIED CORPORATION (US) | 1985-08-14 | — | — | EP | claimed |
| EP-4737458-A2 | PROCESS FOR MAKING CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme LLC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250270197-A1 | RIBOCIL C ANTIBIOTICS EFFECTIVE FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-08-28 | — | — | US | disclosed |
| US-12180198-B2 | Ribocil C antibiotics effective for Gram-negative pathogens | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-12-31 | — | — | US | disclosed |
| CN-113614089-B | Morphinans useful in the treatment of medical conditions | 人福医药美国公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20240190872-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240116911-A1 | RIBOCIL C ANTIBIOTICS EFFECTIVE FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-11 | — | — | US | disclosed |
| EP-0440195-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-4964616-A | USEFUL AS ELECTROOPTICAL MATERIALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0068080-B1 | LIQUID PHASE SYNTHESIS OF HEXAFLUOROISOBUTYLENE | ALLIED CORPORATION (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| US-4227006-A | ANTITHROMBOTICS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1980-10-07 | — | — | US | disclosed |
| US-4179574-A | PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190048280-A1 | Naphthalene-1,8-Dicarboxylate Ester Compounds and Lubricating Oil Base Stocks and Processes for Making Same | NDC1, DGAT1, COQ8B | GAA 3934/4885LMNA 1748/4885ALDH1A1 947/4885 |
| US-20200399197-A1 | Glycol Ether Ester Compounds Useful In Lubricating Oil Compositions And Methods Of Making Same | DEGS1, EBP, GK | GAA 2130/4885LMNA 1676/4885ALDH1A1 667/4885 |
| US-20240116911-A1 | RIBOCIL C ANTIBIOTICS EFFECTIVE FOR GRAM-NEGATIVE PATHOGENS | RPSA, RPS5, RPS2 | GAA 572/4885LMNA 1135/4885ALDH1A1 4408/4885 |
| US-20250270197-A1 | RIBOCIL C ANTIBIOTICS EFFECTIVE FOR GRAM-NEGATIVE PATHOGENS | RPSA, RPS5, RPS2 | GAA 572/4885LMNA 1135/4885ALDH1A1 4408/4885 |
| US-12180198-B2 | Ribocil C antibiotics effective for Gram-negative pathogens | RPSA, RPS5, RPS2 | GAA 572/4885LMNA 1135/4885ALDH1A1 4408/4885 |
| US-10662388-B2 | Ester compounds, lubricating oil compositions containing same and processes for making same | GK, NOTUM, EBP | GAA 2747/4885LMNA 2637/4885ALDH1A1 533/4885 |
| US-20180282257-A1 | Aromatic Monoester Compositions and Processes for Preparing Same | ADH1A, ADH1C, GK | GAA 608/4885LMNA 1583/4885ALDH1A1 142/4885 |
| US-10738259-B2 | Naphthalene-1,8-dicarboxylate ester compounds and lubricating oil base stocks and processes for making same | NDC1, DGAT1, COQ8B | GAA 3934/4885LMNA 1748/4885ALDH1A1 947/4885 |
| US-20240190872-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | DBI, MGAM, MGAM2 | GAA 21/4885LMNA 2381/4885ALDH1A1 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.