Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.38 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.38 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660974 | 0.89 | ANPEP (0.44) | CTSKPSMB5ANPEPRNPEPDNPEP | |
| SCHEMBL8744670 | 0.85 | SLC1A3 (0.41) | CTSKANPEPRNPEPDNPEPLNPEP | |
| SCHEMBL3667251 | 0.84 | CTSK (0.42) | CTSKLNPEPERAP2CTSLCTSS | |
| SCHEMBL27809385 | 0.78 | ANPEP (0.48) | CTSKANPEPRNPEPDNPEPCTSL | |
| SCHEMBL7420644 | 0.77 | ANPEP (0.43) | CTSKANPEPRNPEPDNPEPCTSL | |
| SCHEMBL8586811 | 0.77 | CTSB (0.47) | CTSKPSMB5ANPEPRNPEPDNPEP | |
| SCHEMBL9023544 | 0.76 | SLC15A1 (0.45) | CTSKPSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL724023 | 0.76 | CTSK (0.44) | CTSKANPEPRNPEPDNPEPCTSL | |
| SCHEMBL1014662 | 0.76 | CTSB (0.44) | CTSKPSMB5ANPEPRNPEPDNPEP | |
| SCHEMBL27799677 | 0.75 | ANPEP (0.45) | CTSKANPEPRNPEPDNPEPCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234600-A1 | ANTIBODY FORMULATION | F. Hoffmann-La Roche AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080541-A1 | ANTIBODY FORMULATION | F. HOFFMANN-LA ROCHE AG (CH) | 2009-07-02 | — | — | WO | disclosed |