Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 6/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670286 | 0.90 | HSD17B1 (0.45) | TRPV4TACR1HSD17B1HSD17B2MLYCD | |
| SCHEMBL3671609 | 0.88 | MLYCD (0.52) | TACR1HSD17B1HSD17B2MLYCDMEN1 | |
| SCHEMBL1950917 | 0.85 | PTGDR2 (0.54) | TRPV4 | |
| SCHEMBL3671696 | 0.79 | NAMPT (0.51) | HSD17B1HSD17B2KMT2ATSHRNAMPT | |
| SCHEMBL3671611 | 0.78 | PDK1 (0.54) | TACR1HSD17B1HSD17B2MLYCDMEN1 | |
| SCHEMBL3668571 | 0.77 | GPBAR1 (0.52) | TRPV4TACR1GPBAR1 | |
| SCHEMBL3667568 | 0.76 | MGLL (0.42) | TACR1MEN1KMT2AMGLL | |
| SCHEMBL3666331 | 0.76 | MTOR (0.47) | TACR1MGLLBRAF | |
| SCHEMBL3671898 | 0.76 | LIPE (0.46) | TACR1MGLLBRAF | |
| SCHEMBL3666874 | 0.75 | ABHD6 (0.54) | TACR1HSD17B2MEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |