Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669718 | 0.81 | FABP3 (0.38) | FABP3FABP4FABP5AKR1C3AKR1C2 | |
| SCHEMBL10120473 | 0.71 | GLA (0.47) | AKR1C3AKR1C2MTNR1A | |
| SCHEMBL1896069 | 0.71 | MTNR1A (0.38) | FABP3FABP4FABP5SIRT2MTNR1A | |
| SCHEMBL7353138 | 0.65 | PTGS2 (0.46) | ALDH1A1LMNAKDM4E | |
| SCHEMBL3665020 | 0.65 | FABP3 (0.38) | FABP3FABP4FABP5SIRT2SLC6A2 | |
| SCHEMBL3671725 | 0.65 | AR (0.37) | FABP3FABP4FABP5SIRT2RAB9A | |
| Hydrochloric Acid SCHEMBL3664999 | 0.64 | AR (0.36) | FABP3FABP4FABP5SIRT2RAB9A | |
| SCHEMBL8372932 | 0.63 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTKDM4EHTT | |
| SCHEMBL9404119 | 0.62 | ALDH1A1 (0.39) | NPC1RAB9APOLBCASP3SENP8 | |
| SCHEMBL173444 | 0.62 | MMP12 (0.37) | NPC1RAB9AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056788-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056773-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | claimed |
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2011056773-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011056788-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-05-12 | — | — | WO | disclosed |
| EP-2234960-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | Mayo Foundation for Medical Education and Research (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009089479-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-07-16 | — | — | WO | disclosed |