Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988768 | 0.89 | NPSR1 (0.57) | FABP4NPSR1GPR17TSHRMEN1 | |
| SCHEMBL9336629 | 0.89 | FABP4 (0.45) | FABP4NPSR1GPR17TSHRMAPK1 | |
| SCHEMBL22190396 | 0.83 | MAPK1 (0.55) | FABP4NPSR1TSHRMAPK1HDAC3 | |
| SCHEMBL29009941 | 0.80 | FFAR1 (0.46) | FABP4NPSR1TSHRMEN1KMT2A | |
| SCHEMBL1454248 | 0.79 | TSHR (0.56) | NPSR1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL11392001 | 0.78 | GPR17 (0.42) | NPSR1GPR17MEN1KMT2AHDAC3 | |
| SCHEMBL28045328 | 0.78 | MAPT (0.55) | FABP4MAPK1HDAC3ADRA1AHDAC4 | |
| SCHEMBL11099663 | 0.77 | KDM4E (0.44) | NPSR1GPR17TSHRSLC6A3SMN1; SMN2 | |
| SCHEMBL6017716 | 0.77 | GPR17 (0.41) | NPSR1GPR17MEN1KMT2AKDM4E | |
| SCHEMBL9861837 | 0.76 | HDAC3 (0.52) | NPSR1TSHRMAPK1HDAC3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511707-B1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | SHOWA DENKO KK (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| WO-2007111994-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2007-10-04 | — | — | WO | disclosed |
| US-7115782-B2 | Process for producing aromatic compounds by Friedel-Crafts reaction | SHOWA DENKO K.K. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | SHOWA DENKO K.K. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1511707-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | Showa Denko K.K. (JP) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003101925-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUNDS BY FRIEDEL-CRAFTS REACTION | SHOWA DENKO K. K. (JP) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222457-A1 | Process for producing aromatic compounds by friedel-crafts reaction | PAH, DDC, TYR | FABP4 274/4885NPSR1 2321/4885GPR17 2356/4885 |
| US-20090131384-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | NR1H3, NR1H2, SREBF1 | FABP4 488/4885NPSR1 2102/4885GPR17 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.