Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212067 | 0.87 | GABRG2 (0.44) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 | |
| SCHEMBL27301684 | 0.86 | GABRG2 (0.41) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 | |
| SCHEMBL6972024 | 0.85 | MAPT (0.46) | ALDH1A1MAPTKMT2AIDO1MEN1 | |
| Acetoacetic Acid SCHEMBL27885108 | 0.85 | SMN1; SMN2 (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL14155105 | 0.82 | TLR8 (0.47) | ALDH1A1MAPTKMT2AIDO1MEN1 | |
| SCHEMBL5885533 | 0.81 | LMNA (0.48) | ALDH1A1MAPTKMT2AIDO1MEN1 | |
| SCHEMBL16376886 | 0.81 | GABRG2 (0.58) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 | |
| SCHEMBL28133362 | 0.81 | ABL1 (0.44) | ALDH1A1MAPTKMT2AIDO1MEN1 | |
| SCHEMBL8283686 | 0.81 | FBP1 (0.43) | ALDH1A1MAPTADORA2AKMT2AIDO1 | |
| SCHEMBL5538032 | 0.81 | MAPT (0.38) | GABRG2GABRB3GABRA5GABRA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | claimed |
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |
| CN-107922428-B | Thienopyrrole compounds and their use as inhibitors of oplophorus-derived luciferase | 普洛麦格公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3313846-B1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES | PROMEGA CORP (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | PROMEGA CORPORATION | 2020-02-27 | — | — | US | disclosed |
| WO-2019242689-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2019-12-26 | — | — | WO | disclosed |
| CN-109813699-A | A kind of gaseous aldehyde detection method based on SERS- micro-fluidic chip | 东南大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-108698992-A | 2- cyano isoindoline derivatives for treating cancer | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |
| EP-3313846-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES | Promega Corporation (US) | 2018-05-02 | — | — | EP | disclosed |
| CN-1842516-A | Amide compounds and method for controlling plant diseases using the same | SUMITOMO CHEMICAL CO (JP) | 2006-10-04 | — | — | CN | disclosed |
| WO-2005058871-A1 | MORPHOLINYL CONTAINING BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| EP-0907731-B1 | METABOTROPIC GABA(B) RECEPTORS, RECEPTOR-SPECIFIC LIGANDS AND THEIR USES | NOVARTIS AG (CH) | 2005-03-02 | — | — | EP | disclosed |
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| US-20020091250-A1 | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses | NOVARTIS AG (CH) | 2002-07-11 | — | — | US | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| EP-0907731-A1 | METABOTROPIC GABA(B) RECEPTORS, RECEPTOR-SPECIFIC LIGANDS AND THEIR USES | Novartis AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997046675-A1 | METABOTROPIC GABA[B] RECEPTORS, RECEPTOR-SPECIFIC LIGANDS AND THEIR USES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| US-5276148-A | Phenylazobenzenes or naphthylazobenzenes having a plurality of fiber-reactive groups | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | GABRG2 1830/4885GABRB3 1611/4885GABRA5 1368/4885 |
| US-20020091250-A1 | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses | GABBR1, GABBR2, GABRB1 | GABRG2 15/4885GABRB3 5/4885GABRA5 10/4885 |
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | THOP1, TYMP, CREBBP | GABRG2 1460/4885GABRB3 742/4885GABRA5 1711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.