Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethyl Vanillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Vanillin SCHEMBL434399 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL11126388 | 0.94 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL9652067 | 0.94 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL891376 | 0.94 | ALDH1A1 (0.80) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL20873435 | 0.91 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Vanillin SCHEMBL118411 | 0.90 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Vanillin SCHEMBL4665586 | 0.90 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Vanillin SCHEMBL432750 | 0.90 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL10344524 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATOP2AHPGD | |
| Ethyl Vanillin SCHEMBL28567316 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ATOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139794-A | Membrane and capsule | 联合利华知识产权控股有限公司 | 2024-06-04 | — | — | CN | claimed |
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | claimed |
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| CN-116439403-A | Atomized liquid, atomizer and aerosol generating device | 常州市派腾电子技术服务有限公司 | 2023-07-18 | — | — | CN | claimed |
| US-11504443-B2 | Odor-modulating agent and odor-modulating method | YAMAMOTO PERFUMERY CO., LTD. (JP) | 2022-11-22 | — | — | US | claimed |
| CN-107407046-B | Fibrous element, fibrous structure and product comprising a deterrent agent and methods of making the same | 宝洁公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114672359-A | Lubricating oil | 山本香料株式会社 | 2022-06-28 | — | — | CN | claimed |
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | claimed |
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | claimed |
| CN-101346072-A | Compositions for oral or transdermal delivery providing a heating sensation | CADBURY ADAMS USA LLC (US) | 2009-01-14 | — | — | CN | claimed |
| WO-2007092823-A2 | SIALAGOGUE COATINGS FOR INTERPROXIMAL DEVICES | WHITEHILL ORAL TECHNOLOGIES, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070190090-A1 | SIALAGOGUE BASED ORAL CARE PRODUCTS | WHITEHILL ORAL TECHNOLOGIES, INC. (US) | 2007-08-16 | — | — | US | claimed |
| US-20060177384-A1 | Sialagogue coatings for interproximal devices | WHITEHILL ORAL TECHNOLOGIES, INC. | 2006-08-10 | — | — | US | claimed |
| US-6899901-B2 | Sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-05-31 | — | — | US | claimed |
| US-6890567-B2 | Sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-05-10 | — | — | US | claimed |
| US-6780443-B1 | COMBINATION OF COOLING, WARMING AND TINGLING AGENTS FOR SUCH AS MOUTHWASHES; EMPLOYS JAMBU OLEORESIN AND/OR SPILANTHOL; LONG LASTING | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-24 | — | — | US | claimed |
| US-20040052735-A1 | Sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION | 2004-03-18 | — | — | US | claimed |
| US-20030215532-A1 | New sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION | 2003-11-20 | — | — | US | claimed |
| EP-1121927-A2 | A composition causing different skin sensations | Takasago International Corporation (JP) | 2001-08-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190090-A1 | SIALAGOGUE BASED ORAL CARE PRODUCTS | MUC1, TAS2R40, TAS2R39 | ALDH1A1 3787/4885MEN1 4649/4885KMT2A 4366/4885 |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | CNR2, ADRB2, TRPA1 | ALDH1A1 2031/4885MEN1 529/4885KMT2A 2365/4885 |
| US-20040052735-A1 | Sensate composition imparting initial sensation upon contact | NISCH, OSBP, TRPA1 | ALDH1A1 2316/4885MEN1 980/4885KMT2A 4155/4885 |
| US-20030215532-A1 | New sensate composition imparting initial sensation upon contact | NISCH, OSBP, TRPA1 | ALDH1A1 2579/4885MEN1 1363/4885KMT2A 4305/4885 |
| US-20060177384-A1 | Sialagogue coatings for interproximal devices | TAS2R10, SIGLEC7, TAS2R16 | ALDH1A1 3938/4885MEN1 4780/4885KMT2A 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.