Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365256 | 0.90 | EGFR (0.40) | PKMKMT2AALDH1A1NCEH1RAB9A | |
| SCHEMBL367616 | 0.89 | NCEH1 (0.46) | PKMKMT2AALDH1A1NCEH1RAB9A | |
| SCHEMBL367734 | 0.86 | ATM (0.40) | PKMKMT2AALDH1A1NCEH1RAB9A | |
| SCHEMBL366828 | 0.81 | PKM (0.46) | PKMKMT2AALDH1A1NCEH1RAB9A | |
| SCHEMBL365189 | 0.80 | ACHE (0.37) | ALDH1A1NCEH1ACHES1PR3 | |
| SCHEMBL366116 | 0.80 | CA1 (0.41) | EGFR | |
| SCHEMBL366790 | 0.80 | EGFR (0.41) | KMT2AALDH1A1EGFRSRCMEN1 | |
| SCHEMBL365769 | 0.80 | LTB4R (0.39) | PKMKMT2AALDH1A1LMNATSHR | |
| SCHEMBL367671 | 0.78 | PSEN1 (0.39) | ALDH1A1EGFRTSHR | |
| SCHEMBL365593 | 0.78 | MRGPRX4 (0.39) | PKMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |