Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511906 | 1.00 | CYP19A1 (0.80) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL29386339 | 0.89 | CYP19A1 (1.00) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL10328452 | 0.89 | CYP19A1 (1.00) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL1843348 | 0.89 | ALOX5 (0.65) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL15457886 | 0.89 | CYP19A1 (0.89) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL30834837 | 0.89 | ALOX5 (0.65) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL14071710 | 0.87 | CYP19A1 (0.82) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL10328456 | 0.84 | CYP19A1 (0.65) | CYP19A1NFKB1CYP3A4CYP1A2TSHR | |
| SCHEMBL31275137 | 0.82 | CYP19A1 (0.74) | CYP19A1NFKB1NFKB2RELASLC5A1 | |
| SCHEMBL17536646 | 0.82 | CYP19A1 (0.74) | CYP19A1NFKB1NFKB2RELASLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709521-B2 | Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles | THE COCA-COLA COMPANY (US) | 2014-04-29 | — | — | US | claimed |
| EP-2160103-A1 | SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES | THE COCA-COLA COMPANY (US) | 2010-03-10 | — | — | EP | claimed |
| US-20090053378-A1 | Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles | THE COCA-COLA COMPANY (US) | 2009-02-26 | — | — | US | claimed |
| WO-2008147726-A1 | SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES | THE COCA-COLA COMPANY (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2023278394-A1 | POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-3700352-B1 | AROMA COMPOSITION | SYMRISE AG (DE) | 2021-09-22 | — | — | EP | disclosed |
| US-20200367542-A1 | AROMA COMPOSITION | SYMRISE AG (DE) | 2020-11-26 | — | — | US | disclosed |
| US-10702484-B2 | Use of 3-(3-hydroxy-4-methoxy-phenyl)-1-(2,4,6-trihydroxy-phenyl) propan-1-one | SYMRISE AG (DE) | 2020-07-07 | — | — | US | disclosed |
| US-20190343777-A1 | USE OF 3-(3-HYDROXY-4-METHOXY-PHENYL)-1-(2,4,6-TRIHYDROXY-PHENYL) PROPAN-1-ONE | SYMRISE AG (DE) | 2019-11-14 | — | — | US | disclosed |
| WO-2017186299-A1 | USE OF 3-(3-HYDROXY-4-METHOXY-PHENYL)-1-(2,4,6-TRIHYDROXY-PHENYL)-PROPAN-1-ONE | SYMRISE AG (DE) | 2017-11-02 | — | — | WO | disclosed |
| EP-2160103-B1 | SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES | COCA COLA CO (US) | 2015-07-29 | — | — | EP | disclosed |
| US-8992892-B2 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-one | SYMRISE AG (DE) | 2015-03-31 | — | — | US | disclosed |
| EP-2353403-B1 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on | SYMRISE AG (DE) | 2012-07-11 | — | — | EP | disclosed |
| EP-2353403-A1 | Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on | Symrise AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-20110189108-A1 | USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE | SYMRISE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110189108-A1 | USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE | SYMRISE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20090053378-A1 | Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles | THE COCA-COLA COMPANY (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090053378-A1 | Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles | THE COCA-COLA COMPANY (US) | 2009-02-26 | — | — | US | disclosed |
| US-20090053378-A1 | Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles | THE COCA-COLA COMPANY (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2008147726-A1 | SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES | THE COCA-COLA COMPANY (US) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200367542-A1 | AROMA COMPOSITION | HES1, ADH1C, DHPS | CYP19A1 761/4885NFKB1 3055/4885NFKB2 2885/4885 |
| US-10702484-B2 | Use of 3-(3-hydroxy-4-methoxy-phenyl)-1-(2,4,6-trihydroxy-phenyl) propan-1-one | TAS1R1, TAS1R3, TAS2R40 | CYP19A1 4577/4885NFKB1 3164/4885NFKB2 3555/4885 |
| US-20110189108-A1 | USE OF 1-(2,4-DIHYDROXY-PHENYL)-3-(3-HYDROXY-4-METHOXY-PHENYL)-PROPAN-1-ONE | HES1, TAS2R20, TAS2R50 | CYP19A1 4353/4885NFKB1 743/4885NFKB2 1261/4885 |
| US-20190343777-A1 | USE OF 3-(3-HYDROXY-4-METHOXY-PHENYL)-1-(2,4,6-TRIHYDROXY-PHENYL) PROPAN-1-ONE | TAS1R1, TAS1R3, TAS2R40 | CYP19A1 4577/4885NFKB1 3164/4885NFKB2 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.