Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750661 | 0.83 | CA12 (0.40) | FAAHSOAT1MEN1TP53CYP1A2 | |
| SCHEMBL1545275 | 0.83 | TSHR (0.38) | FAAHZDHHC20ZDHHC2TSHRALDH1A1 | |
| SCHEMBL29191579 | 0.81 | CA12 (0.42) | FAAHTSHRSOAT1MEN1TP53 | |
| SCHEMBL3263644 | 0.81 | ALDH1A1 (0.37) | TSHRALDH1A1MAPT | |
| SCHEMBL7681528 | 0.80 | FAAH (0.39) | FAAHZDHHC20ZDHHC2TSHRALDH1A1 | |
| SCHEMBL9456807 | 0.77 | CA1 (0.46) | ALDH1A1MAPTRAB9ANPSR1KDM5A | |
| SCHEMBL29333 | 0.75 | ZDHHC20 (0.45) | FAAHZDHHC20ZDHHC2TSHRSOAT1 | |
| Bromide SCHEMBL29169641 | 0.74 | FAAH (0.55) | FAAHTSHRMEN1KMT2A | |
| Bromide SCHEMBL29169640 | 0.74 | FAAH (0.55) | FAAHTSHRMEN1KMT2A | |
| SCHEMBL11085445 | 0.74 | ZDHHC20 (0.47) | FAAHZDHHC20ZDHHC2TSHRSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | UNIVERSIDAD DEL PAIS VASCO (ES) | 2009-12-03 | — | — | US | claimed |
| EP-1874723-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | Dominion Pharmakine S.L. (ES) | 2008-01-09 | — | — | EP | claimed |
| WO-2006108864-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2006-10-19 | — | — | WO | claimed |
| US-8097656-B2 | Nitrogenated trans-stilbene analogs, method for the obtention and medical applications thereof | Dominion Pharmakine S.L (ES) | 2012-01-17 | — | — | US | disclosed |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2011-03-10 | — | — | US | disclosed |
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | UNIVERSIDAD DEL PAIS VASCO (ES) | 2009-12-03 | — | — | US | disclosed |
| EP-1874723-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | Dominion Pharmakine S.L. (ES) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108864-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | TNNI3, TNNT2, INMT | FAAH 2526/4885ZDHHC20 1549/4885ZDHHC2 1926/4885 |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | TNNI3, TNNT2, NOS2 | FAAH 2601/4885ZDHHC20 1826/4885ZDHHC2 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.