SCHEMBL3678536

SCHEMBL3678536

Oc1cccc(O)c1/N=N/c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.60
▸ ALDH1A1 P00352 2/20 0.57
▸ MEN1 O00255 8/20 0.56
▸ KMT2A Q03164 8/20 0.56
▸ NPC1 O15118 4/20 0.56
▸ MAPT P10636 7/20 0.52
▸ TDP1 Q9NUW8 4/20 0.52
▸ MAPK1 P28482 3/20 0.52
▸ HSP90AA1 P07900 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ RAB9A P51151 4/20 0.48
▸ LMNA P02545 4/20 0.48
▸ USP2 O75604 1/20 0.48
▸ IDO1 P14902 1/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.47
▸ CASP3 P42574 2/20 0.47
▸ SENP7 Q9BQF6 2/20 0.47
▸ SENP6 Q9GZR1 2/20 0.47
▸ ALPL P05186 1/20 0.47
▸ ALPI P09923 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3487440 1.00 THRB (0.60) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL27575424 0.87 THRB (0.53) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL29419851 0.84 LMNA (0.50) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL3418836 0.82 ALDH1A1 (0.53) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL11317046 0.82 MEN1 (0.58) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL11629954 0.82 MEN1 (0.58) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL29746411 0.82 TDP1 (0.47) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL28259028 0.81 TRIM24 (0.52) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL9657216 0.80 IDO1 (0.51) THRBALDH1A1MEN1KMT2ANPC1
SCHEMBL2230799 0.80 CDK1 (0.44) THRBALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6222074-B1 REDUCING 4,6-BIS(SUBSTITUTED)PHENYLAZORESORCINOL WITH HYDROGEN IN PRESENCE OF METAL CATALYST AND SOLVENT, AND ALIPHATIC NITRILE TO OBTAIN 4,6-DIAMINORESORCINOL OR SALTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-24 — — US claimed
US-4983492-A Positive dye photoresist compositions with 2,4-bis(phenylazo)resorcinol SHIPLEY COMPANY INC. (US) 1991-01-08 — — US claimed
JP-11006090-A — — None — — JP disclosed
CN-115814955-B Zinc collecting agent for improving recovery rate of zinc and rare-earth germanium and beneficiation method 广东省科学院资源利用与稀土开发研究所 2025-09-02 — — CN disclosed
WO-2025018070-A1 RUBBER COMPOSITION NOK株式会社 2025-01-23 — — WO disclosed
CN-115814955-A Zinc collector for improving recovery rate of zinc and rare metal germanium and beneficiation method 广东省科学院资源利用与稀土开发研究所 2023-03-21 — — CN disclosed
CN-111051983-A Positive photosensitive transfer material, method for producing same, and method for producing circuit wiring 富士胶片株式会社 2020-04-21 — — CN disclosed
US-20170209400-A1 METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION LIVIONEX INC (US) 2017-07-27 — — US disclosed
US-9616127-B2 Method and topical formulation for treating localized edema LIVIONEX INC. (US) 2017-04-11 — — US disclosed
US-20100069335-A1 Prevention and Treatment of Ophthalmic Complications of Diabetes LIVIONEX INC. 2010-03-18 — — US disclosed
US-20100063152-A1 Method and Topical Formulation for Treating Localized Edema LIVIONEX INC. 2010-03-11 — — US disclosed
US-5152801-A Exhaust dyeing gives good colorfastness for shoe leather CIBA-GEIGY CORPORATION (US) 1992-10-06 — — US disclosed
US-5116715-A Contrast, resolution, photoresists U C B S.A. (BE) 1992-05-26 — — US disclosed
WO-1991010744-A1 CHROMOGENIC 9-POSITION MODIFIED N-ACETYLNEURAMINIC ACID SUBSTRATES AND METHODS FOR DIAGNOSING HUMAN INFLUENZA THEREWITH SYMEX CORP. (US) 1991-07-25 — — WO disclosed
US-5007941-A Exhaust process; mixture of anionic dye and inorganic pigment CIBA-GEIGY CORPORATION (US) 1991-04-16 — — US disclosed
US-4983492-A Positive dye photoresist compositions with 2,4-bis(phenylazo)resorcinol SHIPLEY COMPANY INC. (US) 1991-01-08 — — US disclosed
EP-0345714-A2 Dyed photoresist compositions and process ASPECT SYSTEMS CORPORATION (US) 1989-12-13 — — EP disclosed
EP-0323427-A2 Light-sensitive compositions with phenol resins and quinone diarides U C B, S.A. (BE) 1989-07-05 — — EP disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 — — US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069335-A1 Prevention and Treatment of Ophthalmic Complications of Diabetes SLC5A1, SLC2A8, SMS THRB 3543/4885ALDH1A1 2737/4885MEN1 178/4885
US-20100063152-A1 Method and Topical Formulation for Treating Localized Edema SLC5A6, SLC39A11, SLC38A7 THRB 4675/4885ALDH1A1 4618/4885MEN1 3411/4885
US-20170209400-A1 METHODS AND TOPICAL FORMULATIONS FOR TREATING INFLAMMATION MMP8, CXCL8, MMP1 THRB 4565/4885ALDH1A1 4592/4885MEN1 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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