Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807056 | 0.93 | ALDH1A1 (0.47) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| Ethylene Glycol SCHEMBL366742 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL3391453 | 0.81 | APOBEC3G (0.39) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| Ethylene Glycol SCHEMBL5450377 | 0.80 | GABRA1 (0.54) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL252950 | 0.79 | KDM4E (0.57) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL7901091 | 0.78 | ALDH1A1 (0.55) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL10394281 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL11801031 | 0.78 | KDM4E (0.47) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL1253668 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ADRB2ADRB1LMNAHTR1A | |
| SCHEMBL4540726 | 0.77 | KDM4E (0.60) | ALDH1A1ADRB2ADRB1LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-8252859-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2012-08-28 | — | — | US | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| CN-101646707-A | Aldimines with reactive groups comprising active hydrogen | SIKA TECHNOLOGY AG CH | 2010-02-10 | — | — | CN | disclosed |
| US-7629433-B2 | Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents | SIKA TECHNOLOGY AG (CH) | 2009-12-08 | — | — | US | disclosed |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | SIKA TECHNOLOGY AG (CH) | 2009-07-09 | — | — | US | disclosed |
| US-20090099333-A1 | Compounds Containing Aldimine | SIKA TECHNOLOGY AG (CH) | 2009-04-16 | — | — | US | disclosed |
| EP-0091453-B1 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES | SINTEF (NO) | 1991-03-13 | — | — | EP | disclosed |
| US-4530956-A | Process for the preparation of aqueous dispersions of organic material and possible further conversion to a polymer dispersion when the organic material is a polymerizable monomer | SINTEF (NO) | 1985-07-23 | — | — | US | disclosed |
| EP-0091453-A1 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES. | SINTEF (NO) | 1983-10-19 | — | — | EP | disclosed |
| WO-1983001453-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF ORGANIC MATERIAL AND OPTIONALLY FURTHER CONVERSION TO A POLYMER DISPERSION | UGELSTAD, JOHN | 1983-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | ALDH1A1 6/4885ADRB2 2057/4885ADRB1 1905/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | ALDH1A1 5/4885ADRB2 2881/4885ADRB1 3273/4885 |
| US-20090176944-A1 | Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof | ADH5, ADH1C, ADH1A | ALDH1A1 5/4885ADRB2 456/4885ADRB1 356/4885 |
| US-20090099333-A1 | Compounds Containing Aldimine | ALDH7A1, ALDH3A1, ALDH1A1 | ALDH1A1 3/4885ADRB2 1294/4885ADRB1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.