Acetamide

Acetamide

SCHEMBL368024

CC(N)=O.Cc1ccc(C(=O)COc2c(C(=O)c3ccc(Cl)c(C)c3Cl)c(C)nn2C)cc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
ABCB1 P08183 2/20 0.35
ENPP3 O14638 1/20 0.34
ALPL P05186 1/20 0.34
XIAP P98170 1/20 0.34
MAPT P10636 6/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
PKM P14618 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
MAPK1 P28482 1/20 0.32
HPGD P15428 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9142685 0.96 ABCB1 (0.37) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL55547 0.96 ABCB1 (0.37) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL27505540 0.95 ABCB1 (0.36) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL11134794 0.88 CA12 (0.36) ALDH1A1ABCB1MAPTKDM4ELMNA
SCHEMBL8466623 0.88 ABCB1 (0.45) ALDH1A1ABCB1MAPTKDM4ELMNA
SCHEMBL13950351 0.88 ABCB1 (0.37) ALDH1A1ABCB1ENPP3ALPLXIAP
3,6 Dichloromethoxybenzoic Acid SCHEMBL17927124 0.87 ALDH1A1 (0.41) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL22946175 0.85 ABCB1 (0.35) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL9291996 0.85 ENPP3 (0.41) ALDH1A1ABCB1ENPP3ALPLXIAP
SCHEMBL11130968 0.82 MAPT (0.42) MAPTKDM4ELMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531670-B1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2015-12-09 EP disclosed
US-8551918-B2 Herbicidal composition SYNGENTA CROP PROTECTION LLC (US) 2013-10-08 US disclosed
US-8097561-B2 Herbicidal composition SYNGENTA CROP PROTECTION, INC. (US) 2012-01-17 US disclosed
CN-100579371-C Herbicidal composition SYNGENTA PARTICIPATIONS AG 2010-01-13 CN disclosed
US-20070197387-A1 Herbicidal Composition SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 US disclosed
EP-1689227-A2 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2006-08-16 EP disclosed
EP-1531670-A4 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-11-23 EP disclosed
US-20050233907-A1 Herbicidal composition SYNGENTA CROP PROTECTION AG (CH) 2005-10-20 US disclosed
CN-1671288-A Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2005-09-21 CN disclosed
WO-2005055716-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 WO disclosed
EP-1531670-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2005-05-25 EP disclosed
WO-2003105587-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2003-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233907-A1 Herbicidal composition ADH5, ADH1C, AQP3 ALDH1A1 81/4885ABCB1 1645/4885ENPP3 1077/4885
US-20070197387-A1 Herbicidal Composition DDT, HDHD5, DERL1 ALDH1A1 1746/4885ABCB1 150/4885ENPP3 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.