Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857516 | 0.99 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL13857523 | 0.99 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL3685299 | 0.89 | MGLL (0.34) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL10456409 | 0.81 | NPC1 (0.46) | ALDH1A1GAALMNAL3MBTL1MAPT | |
| SCHEMBL13857524 | 0.81 | CES2 (0.39) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL13857528 | 0.77 | PKM (0.42) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL3680690 | 0.77 | CES2 (0.47) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL13857529 | 0.76 | KDM4E (0.31) | ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL31055049 | 0.75 | KDM4E (0.68) | ALDH1A1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL13857530 | 0.74 | KDM4E (0.32) | ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | ALDH1A1 236/4885KDM4E 1405/4885GAA 953/4885 |
| US-20090137789-A1 | Oligonucleotide Probes | NCL, RNGTT, NSUN3 | ALDH1A1 2227/4885KDM4E 4808/4885GAA 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.