Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450310 | 0.80 | CES1 (0.48) | THRBCES1ALDH1A1MAPK1HIF1A | |
| SCHEMBL1261037 | 0.80 | THRB (0.46) | THRBCES1ALDH1A1MAPK1HIF1A | |
| SCHEMBL19846629 | 0.79 | THRB (0.51) | THRBALDH1A1MAPK1HIF1ATP53 | |
| SCHEMBL9718678 | 0.79 | ALDH1A1 (0.41) | CES1ALDH1A1MAPK1HIF1ACYP3A4 | |
| SCHEMBL19469257 | 0.78 | THRB (0.49) | THRBCES1ALDH1A1MAPK1HIF1A | |
| SCHEMBL18051656 | 0.78 | THRB (0.47) | THRBALDH1A1MAPK1HIF1ATP53 | |
| SCHEMBL9848771 | 0.77 | THRB (0.54) | THRBCES1ALDH1A1MAPK1HIF1A | |
| SCHEMBL1724042 | 0.76 | THRB (0.49) | THRBALDH1A1MAPK1HIF1ATP53 | |
| SCHEMBL28771131 | 0.76 | THRB (0.45) | THRBALDH1A1MAPK1HIF1ATP53 | |
| SCHEMBL197860 | 0.76 | ALDH1A1 (0.56) | CES1ALDH1A1MAPK1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791289-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-07-29 | — | — | US | disclosed |
| US-8791289-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-07-29 | — | — | US | disclosed |
| US-8791289-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-07-29 | — | — | US | disclosed |
| US-8664431-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-03-04 | — | — | US | disclosed |
| US-8664431-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-03-04 | — | — | US | disclosed |
| US-8664431-B2 | Preparation method of copolymerizable photoinitiators | AGFA GRAPHICS NV (BE) | 2014-03-04 | — | — | US | disclosed |
| US-20140024840-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2014-01-23 | — | — | US | disclosed |
| US-20140024840-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2014-01-23 | — | — | US | disclosed |
| US-20140024840-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2014-01-23 | — | — | US | disclosed |
| US-20100305336-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305336-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305336-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2010-12-02 | — | — | US | disclosed |
| WO-2009068590-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | AGFA GRAPHICS NV (BE) | 2009-06-04 | — | — | WO | disclosed |
| EP-2065362-A1 | Preparation method of copolymerizable photoinitiators | Agfa Graphics N.V. (BE) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305336-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | HBB, HBZ, HBG1 | THRB 481/4885CES1 744/4885ALDH1A1 390/4885 |
| US-20140024840-A1 | PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS | HBB, HBZ, HBG1 | THRB 508/4885CES1 759/4885ALDH1A1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.