Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL9305713 | 1.00 | TP53 (0.44) | TP53SLC22A16BBOX1CA1CA4 | |
| L-Lactic Acid SCHEMBL9312891 | 0.97 | TP53 (0.42) | TP53SLC22A16BBOX1CA1CA4 | |
| L-Lactic Acid SCHEMBL3820373 | 0.88 | BBOX1 (0.41) | TP53SLC22A16BBOX1CA1CA4 | |
| L-Lactic Acid SCHEMBL27503017 | 0.87 | — | — | |
| L-Lactic Acid SCHEMBL3767829 | 0.86 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL7515818 | 0.86 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL992199 | 0.86 | — | — | |
| L-Lactic Acid SCHEMBL21815670 | 0.86 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL22341771 | 0.86 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL152527 | 0.86 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658802-A | Method for preparing lactate by catalyzing alcoholysis of polylactic acid by ionic liquid | 中国科学院化学研究所 | 2024-03-08 | — | — | CN | claimed |
| CN-117658794-A | Method for preparing lactic acid by catalyzing polylactic acid hydrolysis through ionic liquid | 中国科学院化学研究所 | 2024-03-08 | — | — | CN | claimed |
| CN-117623968-A | Method for preparing N-substituted lactamide by catalyzing polylactic acid aminolysis with ionic liquid | 中国科学院化学研究所 | 2024-03-01 | — | — | CN | claimed |
| CN-110585860-A | Low-energy-consumption regenerated absorbent and method for absorbing sulfur dioxide in flue gas by using same | 太原师范学院 | 2019-12-20 | — | — | CN | claimed |
| CN-103079407-A | Improved insecticidal compositions comprising cyclic carboximidamidines | BAYER CROPSCIENCE AG | 2013-05-01 | — | — | CN | claimed |
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | US | claimed |
| US-6277799-B1 | AQUEOUS MIXTURE OF SALT OF HYDROXYCARBOXYLIC ACID AND SURFACTANTS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-08-21 | — | — | US | claimed |
| US-12594700-B2 | Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes | COVESTRO DEUTSCHLAND AG (DE) | 2026-04-07 | — | — | US | disclosed |
| US-20250388778-A1 | POLYISOCYANATE MIXTURE | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-25 | — | — | US | disclosed |
| US-12492281-B2 | Polyisocyanurate materials as electrical potting compounds | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-09 | — | — | US | disclosed |
| CN-120118300-A | Polycarbonate copolymer and preparation method and application thereof | 华东理工大学 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551634-A1 | POLYISOCYANATE MIXTURE | Covestro Deutschland AG (DE) | 2025-05-14 | — | — | EP | disclosed |
| EP-3688050-B1 | TWO-COMPONENT SYSTEM FOR ELASTIC COATINGS | COVESTRO DEUTSCHLAND AG (DE) | 2025-03-26 | — | — | EP | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5576459-A | Quaternary nitrogen or phosphorus chirates | SACHEM, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5371001-A | Transesterification in the presence of carboxy-esterases or carboxyamidases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5326887-A | Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| US-5254718-A | Using enzyme catalyst; simplified separation, purification | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1992015572-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |
| WO-1992015547-A1 | ESTERS OF UNSYMMETRICALLY 2-SUBSTITUTED GLYCOLIC ACID DIMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388778-A1 | POLYISOCYANATE MIXTURE | IPO11, IPO5, ALKBH1 | TP53 2565/4885SLC22A16 1412/4885BBOX1 1793/4885 |
| US-12594700-B2 | Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes | TST, C9, ESD | TP53 4587/4885SLC22A16 2401/4885BBOX1 1883/4885 |
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | DDT, PRMT9, PNISR | TP53 4746/4885SLC22A16 3743/4885BBOX1 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.