Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309628 | 1.00 | ANPEP (0.49) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL13088683 | 0.82 | SIGMAR1 (0.50) | ANPEPMEN1KMT2ATDP1MAOA | |
| SCHEMBL25343744 | 0.80 | MEN1 (0.52) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL3701547 | 0.79 | MEN1 (0.56) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL3079282 | 0.78 | DNM1 (0.57) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10533348 | 0.78 | DNM1 (0.57) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL23134555 | 0.78 | ANPEP (0.55) | ANPEPMEN1KMT2AALDH1A1DNM1 | |
| SCHEMBL1408234 | 0.77 | ANPEP (0.57) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6990126 | 0.77 | ALDH1A1 (0.53) | ANPEPMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6990134 | 0.77 | ALDH1A1 (0.53) | ANPEPMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2026-05-28 | — | — | US | disclosed |
| US-20250101011-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2025-03-27 | — | — | US | disclosed |
| EP-4450497-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd (CN) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |
| WO-2015155306-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2015-10-15 | — | — | WO | disclosed |
| EP-1765789-B1 | N-(1-(1-BENZYL-4-PHENYL-1H-IMIDAZOL-2-YL)-2,2-DIMETHYLPROPYL)BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS KINESIN SPINDLE PROTEIN (KSP) INHIBITORS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| EP-2515657-A1 | TYROSINE KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-10-18 | — | — | US | disclosed |
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-10-18 | — | — | US | disclosed |
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2012-10-18 | — | — | US | disclosed |
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264735-A1 | TYROSINE KINASE INHIBITORS | ABL1, MET, ERBB2 | ANPEP 2056/4885MEN1 1349/4885KMT2A 720/4885 |
| US-20250101011-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | CTSC, CTSL, CTRL | ANPEP 18/4885MEN1 2152/4885KMT2A 4482/4885 |
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | JAK1, CTSZ, CTSL | ANPEP 99/4885MEN1 3993/4885KMT2A 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.