Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 4/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 4/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 4/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 4/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 2/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nylidrin SCHEMBL15517085 | 1.00 | HIF1A (1.00) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL159150 | 1.00 | HIF1A (1.00) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL364078 | 0.99 | ADRA1A (1.00) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL15512520 | 0.97 | HIF1A (0.95) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| SCHEMBL17565768 | 0.89 | SLC6A2 (0.80) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL13724281 | 0.85 | ADRB2 (0.73) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL9352972 | 0.83 | ADRA1A (0.71) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Bufeniode SCHEMBL309865 | 0.82 | ADRA1A (0.70) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| Nylidrin SCHEMBL5697000 | 0.81 | ADRA1A (0.68) | HIF1AADRA1ASLC6A2OPRM1ADRB2 | |
| SCHEMBL19329976 | 0.80 | HIF1A (0.67) | HIF1AADRA1ASLC6A2OPRM1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009934-A1 | BETA ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2010-01-14 | — | — | US | disclosed |
| US-4188404-A | NYLIDRIN HYDROCHLORIDE | USV PHARMACEUTICAL CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |
| US-4086363-A | PARA-HYDROXY-N-(1-METHYL-3-PHENYLPROPYL)-NOREPHEDRINE | USV PHARMACEUTICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4086363-A | PARA-HYDROXY-N-(1-METHYL-3-PHENYLPROPYL)-NOREPHEDRINE | USV PHARMACEUTICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009934-A1 | BETA ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS | ADRB1, ADRB2, ADRA2B | HIF1A 2121/4885ADRA1A 9/4885SLC6A2 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.