Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708760 | 0.92 | KDM4E (0.47) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL3698514 | 0.89 | FABP4 (0.40) | IDO1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3714028 | 0.84 | ALDH1A1 (0.46) | IDO1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3135452 | 0.75 | BCAT2 (0.47) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL3701694 | 0.73 | BCAT2 (0.46) | ALDH1A1MEN1KMT2APOLBHPGD | |
| Hydrochloric Acid SCHEMBL29287793 | 0.73 | CA1 (0.47) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| Hydrochloric Acid SCHEMBL29287828 | 0.73 | CA1 (0.47) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL28568958 | 0.72 | HSP90AA1 (0.46) | PDCD1CD274 | |
| SCHEMBL28568956 | 0.72 | HSP90AA1 (0.46) | PDCD1CD274 | |
| SCHEMBL3704899 | 0.71 | PARP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197835-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | Prosidion Limited (GB) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030962-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |