Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704897 | 0.92 | IDO1 (0.42) | KDM4EALDH1A1HPGDSOAT1KDM6B | |
| SCHEMBL3698514 | 0.87 | FABP4 (0.40) | KDM4EALDH1A1HPGDSOAT1MAPT | |
| SCHEMBL3714028 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHDAC1HDAC8 | |
| SCHEMBL28163070 | 0.76 | MAPT (0.50) | KDM4EALDH1A1HPGDSOAT1CNR2 | |
| SCHEMBL3135452 | 0.73 | BCAT2 (0.47) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL3708765 | 0.72 | FAAH (0.43) | KDM4EALDH1A1HPGDHCAR3SMN1; SMN2 | |
| SCHEMBL3701694 | 0.71 | BCAT2 (0.46) | ALDH1A1HPGDMAPTMEN1POLB | |
| Hydrochloric Acid SCHEMBL29287793 | 0.71 | CA1 (0.47) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL29287828 | 0.71 | CA1 (0.47) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL4785901 | 0.71 | BCAT2 (0.51) | KDM4EALDH1A1HPGDSOAT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197835-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | Prosidion Limited (GB) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030962-A1 | BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |