Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705026 | 0.84 | TSHR (0.50) | ALDH1A1TSHRPKMHTTSMN1; SMN2 | |
| SCHEMBL13735978 | 0.74 | CYP3A4 (0.41) | ALDH1A1TSHRHPGDHTTSMN1; SMN2 | |
| SCHEMBL18415441 | 0.73 | TAS1R3 (0.67) | ALDH1A1APLNRTAS1R3TAS1R1TSHR | |
| SCHEMBL2261220 | 0.72 | APLNR (0.65) | ALDH1A1APLNRTAS1R3TAS1R1TSHR | |
| SCHEMBL10141758 | 0.72 | APLNR (0.65) | ALDH1A1APLNRTAS1R3TAS1R1TSHR | |
| SCHEMBL2223385 | 0.72 | ALDH1A1 (0.59) | ALDH1A1APLNRTAS1R3TAS1R1TSHR | |
| SCHEMBL3707448 | 0.71 | QPCT (0.62) | HTR2ASLC6A4KCNH2ALDH1A1APLNR | |
| SCHEMBL3361891 | 0.71 | APLNR (0.63) | ALDH1A1APLNRTAS1R3TAS1R1TSHR | |
| SCHEMBL23985899 | 0.71 | TAS1R3 (0.71) | ALDH1A1TAS1R3TAS1R1TSHRNPSR1 | |
| SCHEMBL15758317 | 0.71 | KMT2A (0.54) | HTR2ASLC6A4KCNH2ALDH1A1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086613-A1 | COMPOUNDS USEFUL AS INHIBITORS AS AMPK | BETAGENON AB (SE) | 2010-08-05 | — | — | WO | disclosed |