Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725653 | 0.90 | CDK2 (0.46) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3724956 | 0.89 | CDK2 (0.42) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3720176 | 0.88 | TACR2 (0.49) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3726417 | 0.87 | TACR2 (0.42) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL2910733 | 0.86 | CDK2 (0.52) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3721963 | 0.85 | P2RX7 (0.41) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3716187 | 0.84 | CDK2 (0.43) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3718665 | 0.84 | CDK1 (0.44) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3714764 | 0.83 | CDK2 (0.58) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL3724809 | 0.83 | CDK2 (0.40) | CDK2CCNE1CCNE2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139288-A1 | 5,7-DISUBSTITUTED 3-ISOPROPYLPYRAZOLO[4,3-D]PYRIMIDINES FOR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS | C3 BIO GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |