SCHEMBL5784635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3829666	0.86	P2RX7 (0.45)	P2RX7HTR2ALRRK2LTB4RLTB4R2
	SCHEMBL5801145	0.74	LPL (0.44)	P2RX7
	SCHEMBL3404302	0.72	BACE1 (0.37)	MEN1KMT2ALMNAMAPTSMN1; SMN2
	SCHEMBL24915634	0.71	LTB4R (0.45)	P2RX7HTR2ALTB4RLTB4R2DRD2
	SCHEMBL506553	0.71	PDPK1 (0.46)	HTR2ALTB4RLTB4R2
	Hydrochloric Acid SCHEMBL30799506	0.69	PDPK1 (0.44)	HTR2A
	SCHEMBL6369306	0.68	ADRA2A (0.58)	P2RX7LTB4RLTB4R2
	SCHEMBL5019356	0.67	HTR2A (0.48)	HTR2ALTB4RLTB4R2HTR2B
	SCHEMBL8050815	0.66	P2RX7 (0.46)	MEN1KMT2ALMNAGAAMAPT
	SCHEMBL31704396	0.66	MAPK1 (0.47)	P2RX7LTB4RLTB4R2HTR2BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.