Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566383 | 0.78 | KDM4E (0.42) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7146697 | 0.78 | FBP1 (0.47) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL15739862 | 0.78 | RAB9A (0.42) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3721048 | 0.78 | ALDH1A1 (0.47) | GAASMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL11238301 | 0.78 | PDPK1 (0.42) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL19219056 | 0.77 | LMNA (0.46) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL5573502 | 0.76 | HSD17B1 (0.61) | SMN1; SMN2RAB9ATP53NFKB1NFKB2 | |
| SCHEMBL3225350 | 0.76 | KDM4E (0.45) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL10162230 | 0.75 | NPC1 (0.45) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12925903 | 0.74 | RAB9A (0.51) | MAPTSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022846-A1 | COMPOUNDS ENHANCING ANTITUMOR ACTIVITY OF OTHER CYTOTOXIC AGENTS | PFIZER INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0364923-A2 | Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1990-04-25 | — | — | EP | disclosed |