Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721759 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1PTPN1PDE7ATBXA2R | |
| SCHEMBL1390796 | 0.74 | MEN1 (0.35) | ALDH1A1PTPN1MAPTKMT2ANPSR1 | |
| SCHEMBL3726439 | 0.70 | ACACB (0.39) | KDM4EMAPTKMT2AMEN1ACACB | |
| SCHEMBL3716937 | 0.67 | AKR1C3 (0.51) | MAPTKMT2AMEN1ACACBAKR1C3 | |
| SCHEMBL13077221 | 0.63 | ACACB (0.57) | LMNAACACBAKR1C3AKR1C2 | |
| SCHEMBL22069593 | 0.62 | PDE7A (0.74) | KDM4EALDH1A1CYP3A4PDE7AMAPT | |
| SCHEMBL27708666 | 0.62 | PTGS2 (0.57) | KDM4EALDH1A1CYP3A4PDE7ATBXA2R | |
| SCHEMBL3726441 | 0.62 | RAB9A (0.38) | KDM4EMAPTACACB | |
| SCHEMBL23014061 | 0.61 | ALDH1A1 (0.45) | KDM4EALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL11163357 | 0.60 | ALDH1A1 (0.54) | KDM4EALDH1A1PDE7AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |