Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24530453 | 0.85 | ALDH1A3 (0.57) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31664398 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A3ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL12885258 | 0.81 | ALDH1A1 (0.41) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12540995 | 0.81 | ALDH1A1 (0.55) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28884153 | 0.80 | ABL1 (0.39) | ALDH1A3ALDH1A1ERN1TDP1TSHR | |
| SCHEMBL6467176 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EERN1TDP1TSHR | |
| SCHEMBL18812102 | 0.80 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14285929 | 0.80 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28586018 | 0.80 | ACHE (0.51) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL28055985 | 0.80 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195944-A | ester compound and use thereof | 大日本除虫菊株式会社 | 2019-01-11 | — | — | CN | disclosed |
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |
| US-9592221-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-15 | — | — | US | disclosed |
| US-9315495-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315495-B2 | Antibacterial agents: aryl myxopyronin derivatives | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | PROVID PHARMACEUTICALS INC. | 2015-07-16 | — | — | US | disclosed |
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | PROVID PHARMACEUTICALS INC. | 2015-07-16 | — | — | US | disclosed |
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263083-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | POLRMT, POLR1C, FBL | ALDH1A3 3398/4885ALDH1A1 1785/4885KDM4E 2085/4885 |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | ALDH1A3 994/4885ALDH1A1 276/4885KDM4E 1375/4885 |
| US-20150197512-A1 | ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES | FBL, POLRMT, POLR1C | ALDH1A3 3058/4885ALDH1A1 1561/4885KDM4E 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.