Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719950 | 0.87 | MTNR1A (0.38) | — | |
| SCHEMBL3720218 | 0.81 | DUT (0.43) | — | |
| SCHEMBL3720107 | 0.80 | MTNR1A (0.54) | ALDH1A1HPGD | |
| SCHEMBL3720199 | 0.80 | MTNR1A (0.52) | ALDH1A1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL3720089 | 0.77 | TEC (0.37) | — | |
| SCHEMBL3726999 | 0.77 | GPR4 (0.39) | SMN1; SMN2 | |
| SCHEMBL3719580 | 0.75 | ACACB (0.38) | — | |
| SCHEMBL3720928 | 0.74 | SCN7A (0.38) | — | |
| SCHEMBL3717025 | 0.72 | PARP10 (0.40) | — | |
| SCHEMBL3727742 | 0.72 | P2RX3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |