Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723935 | 0.83 | MCL1 (0.39) | OPRD1 | |
| SCHEMBL3722537 | 0.82 | OPRM1 (0.39) | CHRM3OPRM1CA12CA1CA2 | |
| SCHEMBL3724780 | 0.79 | TAS2R14 (0.44) | — | |
| SCHEMBL3726385 | 0.79 | MEN1 (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3727160 | 0.78 | RORC (0.38) | — | |
| SCHEMBL4784868 | 0.78 | PLD2 (0.42) | CHRM2CHRM3OPRM1OPRK1ADRA1A | |
| SCHEMBL3806319 | 0.77 | CHRM5 (0.36) | MEN1KMT2A | |
| SCHEMBL3724470 | 0.76 | HTR2A (0.37) | OPRM1KMT2A | |
| SCHEMBL4828312 | 0.74 | CHRM2 (0.40) | CHRM2CHRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL3725056 | 0.73 | HSD11B1 (0.42) | CHRM2CHRM3OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |