Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035746 | 0.84 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3SGMS2TACR1 | |
| SCHEMBL6749962 | 0.81 | ALOX5 (0.47) | SLC6A2SLC6A4SLC6A3SGMS2MAOB | |
| SCHEMBL11864549 | 0.81 | MAOB (0.53) | SLC6A2SLC6A4SGMS2MAOBIDO1 | |
| SCHEMBL1200547 | 0.80 | TSHR (0.42) | SLC6A2SLC6A4SLC6A3TSHRTRPA1 | |
| SCHEMBL2673956 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRCHRNB2 | |
| SCHEMBL16864534 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRMAOB | |
| SCHEMBL27836981 | 0.80 | TSHR (0.42) | SLC6A2SLC6A4SLC6A3TSHRTRPA1 | |
| SCHEMBL4775948 | 0.80 | TRPA1 (0.47) | SLC6A2SLC6A4SLC6A3SGMS2TSHR | |
| SCHEMBL7537198 | 0.80 | CHRNB2 (0.50) | SLC6A2SLC6A4SLC6A3SGMS2TSHR | |
| SCHEMBL1827514 | 0.79 | CA1 (0.40) | MAOBALDH1A1KMT2ACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304578-B2 | Process for producing 1-[2-(dimethylamino)-1-(4-phenol)ethyl]cyclohexanol | MATRIX LABORATORIES LIMITED (IN) | 2012-11-06 | — | — | US | claimed |
| US-20100286447-A1 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | claimed |
| WO-2009084039-A2 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2009-07-09 | — | — | WO | claimed |
| CN-106349105-B | A kind of preparation method of benzyl cyanide | 河北诚信集团有限公司 | 2018-11-27 | — | — | CN | disclosed |
| US-8304578-B2 | Process for producing 1-[2-(dimethylamino)-1-(4-phenol)ethyl]cyclohexanol | MATRIX LABORATORIES LIMITED (IN) | 2012-11-06 | — | — | US | disclosed |
| US-20100286447-A1 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | disclosed |
| WO-2009084039-A2 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | MATRIX LABORATORIES LIMITED (IN) | 2009-07-09 | — | — | WO | disclosed |
| US-7276526-B2 | Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| CN-1984892-A | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2007-06-20 | — | — | CN | disclosed |
| US-20030114502-A1 | Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2003006015-A1 | SUBSTITUTED THIAZOLES AND OXAZOLES AS CORTICOTROPIN RELEASING HORMONE LIGANDS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-01-23 | — | — | WO | disclosed |
| US-4412082-A | Method for preparing 4-hydroxyphenylacetic acid | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114502-A1 | Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands | CRH, CRHR1, CRHR2 | SLC6A2 555/4885SLC6A4 349/4885SLC6A3 450/4885 |
| US-20100286447-A1 | PROCESS FOR PRODUCING 1-[2-(DIMETHYLAMINO)-1-(4-PHENOL)ETHYL]CYCLOHEXANOL | COMT, HTR1A, TPH1 | SLC6A2 97/4885SLC6A4 46/4885SLC6A3 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.