Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | CA3 | P07451 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533812 | 0.84 | TXNRD1 (0.42) | AGTR1KMT2AHSP90AA1CXCR5APLNR | |
| SCHEMBL27399885 | 0.82 | NCF1 (0.41) | AGTR1KMT2AHSP90AA1CXCR5APLNR | |
| SCHEMBL1976807 | 0.78 | GAA (0.52) | KMT2AHSP90AA1CXCR5APLNRRAB9A | |
| SCHEMBL6820319 | 0.78 | HTR6 (0.48) | AGTR1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL4730663 | 0.75 | AKR1B1 (0.33) | — | |
| SCHEMBL2054702 | 0.74 | CA1 (0.41) | CA1CA2CA9CA12GAA | |
| SCHEMBL11855965 | 0.74 | CA2 (0.67) | AGTR1KMT2ACA1CA2CA9 | |
| SCHEMBL3158508 | 0.74 | CA2 (0.67) | AGTR1KMT2ACA1CA2CA9 | |
| SCHEMBL11419996 | 0.74 | CA2 (0.67) | AGTR1KMT2ACA1CA2CA9 | |
| SCHEMBL4006032 | 0.71 | XDH (0.51) | KMT2ARAB9AGFERCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022215745-A1 | SUBSTANCE OF NOVEL SIDEROPHORE-TYPE ANTIFUNGAL AGENT (COMPOUND) AND USE OF SAME | 国立研究開発法人理化学研究所 | 2022-10-13 | — | — | WO | disclosed |
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090233366-A1 | COMPOSITION FOR INTRODUCTION OF NUCLEIC ACID | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2080767-A1 | COMPOSITION FOR INTRODUCTION OF NUCLEIC ACID | Daiichi Sankyo Company, Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20090022782-A1 | Blood Retainable Device Exhibiting Selective Degradability in Tumor Tissue | NATIONAL UNIVERSITY CORP. HOKKAIDO UNIVERSITY (JP) | 2009-01-22 | — | — | US | disclosed |
| US-7396930-B2 | making spiro(benzo(c)thiophene-1 (3H),4'-piperidine) derivatives; involves reacting a mercapto compound with a 2-halophenylalkyl halide, reacting with an alkyllithium, then N-ethoxycarbonyl-4-piperidone, dehydration and cyclization; industrial scale; novel intermediates to neurokinin receptor antagonist | SANKYO COMPANY, LIMITED (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-1889835-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-1862470-A1 | ELEMENT RETAINED IN BLOOD SHOWING DEGRADABILITY SELECTIVELY IN TUMOR TISSUE | National University Corporation Hokkaido University (JP) | 2007-12-05 | — | — | EP | disclosed |
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-11 | — | — | US | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5451688-A | Inhibit biosynthesis of cholesterol | SANKYO COMPANY, LIMITED (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-4474947-A | Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes | BIOSEARCH (US) | 1984-10-02 | — | — | US | disclosed |
| US-4426517-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4419509-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4417046-A | Process for isolating oligonucleotide product from a coupling reaction mixture | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0075392-A1 | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |
| EP-0002322-A2 | Improved Triester process for the synthesis of oligonucleotides | GENENTECH, INC. (US) | 1979-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010695-A1 | Diphosphines, preparation and uses thereof | MPI, ITPA, DCPS | AGTR1 4344/4885KMT2A 3070/4885HSP90AA1 4560/4885 |
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | CBR3, CNR1, C3AR1 | AGTR1 379/4885KMT2A 2696/4885HSP90AA1 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.