Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795696 | 0.73 | ALDH1A1 (0.42) | FAAHMGLLGAATSHRALDH1A1 | |
| SCHEMBL27620067 | 0.64 | LPO (0.39) | FAAHMGLLGAATSHRALDH1A1 | |
| SCHEMBL217356 | 0.63 | ALDH1A1 (0.42) | FAAHMGLLTSHRALDH1A1POLB | |
| SCHEMBL10985089 | 0.60 | ALDH1A1 (0.72) | FAAHMGLLGAATSHRALDH1A1 | |
| SCHEMBL1684895 | 0.60 | — | — | |
| SCHEMBL22304265 | 0.59 | FAAH (0.66) | FAAHMGLLGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL23024744 | 0.58 | NOS1 (0.48) | ALDH1A1SMN1; SMN2LMNAMAPTHSD17B10 | |
| SCHEMBL6077631 | 0.57 | — | — | |
| SCHEMBL2223429 | 0.57 | TSHR (0.63) | GAATSHRALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1109685 | 0.57 | ALDH1A1 (0.43) | GAATSHRALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |