Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503869 | 0.81 | HTT (0.54) | ALDH1A1TSHRHTTSMN1; SMN2LMNA | |
| SCHEMBL18503870 | 0.75 | KEAP1 (0.54) | ALDH1A1TSHRHTTSMN1; SMN2L3MBTL1 | |
| Malonic Acid SCHEMBL30741151 | 0.69 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2LMNAL3MBTL1NAPRT | |
| SCHEMBL7537309 | 0.68 | KDM4E (0.50) | TSHRLMNAL3MBTL1P4HTMKDM4E | |
| SCHEMBL4685420 | 0.67 | NFE2L2 (0.47) | ALDH1A1TSHRHTTLMNAL3MBTL1 | |
| SCHEMBL28751128 | 0.67 | KEAP1 (0.48) | ALDH1A1TSHRHTTLMNAL3MBTL1 | |
| SCHEMBL10438614 | 0.67 | KAT6A (0.63) | L3MBTL1KAT6AKMT2A | |
| SCHEMBL333243 | 0.66 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2LMNACYP3A4HPGD | |
| SCHEMBL29499090 | 0.66 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2LMNACYP3A4HPGD | |
| Succinic Acid SCHEMBL28112695 | 0.66 | NOS3 (0.64) | ALDH1A1SMN1; SMN2LMNAL3MBTL1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2052011-B1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | STARPHARMA PTY LTD (AU) | 2020-11-04 | — | — | EP | disclosed |
| US-9127130-B2 | Polylysine dendrimer contrast agent | STARPHARMA PTY LTD. (AU) | 2015-09-08 | — | — | US | disclosed |
| US-8420067-B2 | Targeted polylysine dendrimer therapeutic agent | STARPHARMA PTY LTD (AU) | 2013-04-16 | — | — | US | disclosed |
| US-20100292148-A1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | STARPHARMA PTY LTD. (AU) | 2010-11-18 | — | — | US | disclosed |
| US-20100278750-A1 | POLYLYSINE DENDRIMER CONTRAST AGENT | STARPHARMA PTY LTD | 2010-11-04 | — | — | US | disclosed |
| EP-2076557-A1 | POLYLYSINE DENDRIMER CONTRAST AGENT | Starpharma Pty Ltd (AU) | 2009-07-08 | — | — | EP | disclosed |
| EP-2052011-A1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | Starpharma Pty Ltd (AU) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008017125-A1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | STARPHARMA PTY LTD (AU) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017122-A1 | POLYLYSINE DENDRIMER CONTRAST AGENT | STARPHARMA PTY LTD (AU) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278750-A1 | POLYLYSINE DENDRIMER CONTRAST AGENT | PARG, PARN, TLR3 | ALDH1A1 4386/4885TSHR 3322/4885HTT 917/4885 |
| US-20100292148-A1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | CLTA, PARG, FLT3 | ALDH1A1 4285/4885TSHR 4133/4885HTT 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.