SCHEMBL374679

SCHEMBL374679

CCCCCCCCCCCCCCCCCC(=O)OC(O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.63
MAPT P10636 2/20 0.59
MAPK1 P28482 1/20 0.59
ALDH1A1 P00352 1/20 0.56
DGKA P23743 1/20 0.52
FFAR4 Q5NUL3 1/20 0.52
FFAR1 O14842 1/20 0.52
PRKCA P17252 1/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
KDM4E B2RXH2 1/20 0.50
DUSP3 P51452 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28509949 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL29750264 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL28825036 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL2134678 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL28901085 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL11538562 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL10879135 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL10880392 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL17969541 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA
SCHEMBL28117236 1.00 LMNA (0.63) LMNAMAPTMAPK1ALDH1A1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 916 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023208523-A1 COMPOSITION WITH A POLYPHENOL, AN AQUEOUS DISPERSION OF WAX, A NONIONIC SURFACTANT WITH AN HLB OF GREATER THAN OR EQUAL TO 8 AND AN UNCOATED IRON OXIDE L'OREAL (FR) 2023-11-02 WO claimed
CN-113316473-B Cosmetic O/W mascara composition comprising polyurethane resin 布茨公司 2023-09-08 CN claimed
EP-3682948-B1 COSMETIC O/W MASCARA COMPOSITIONS COMPRISING POLYURETHANE RESIN BOOTS CO PLC (GB) 2023-08-30 EP claimed
CN-115844740-A Superfine eyebrow pencil and manufacturing method thereof 娇时日化(杭州)股份有限公司 2023-03-28 CN claimed
EP-2863996-B1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C OREAL (FR) 2021-03-24 EP claimed
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS L'OREAL (FR) 2020-03-26 US claimed
US-10576031-B1 Exfoliating and hydrating makeup removing compositions L'OREAL (FR) 2020-03-03 US claimed
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius L'OREAL (FR) 2019-11-12 US claimed
EP-1920757-B1 Cosmetic composition containing citric acid derivatives ORÉAL L (FR) 2016-05-11 EP claimed
WO-2016058180-A1 SOLID ANHYDROUS COMPOSITION FOR REMOVING THE MAKEUP ON THE SKIN L'OREAL (FR) 2016-04-21 WO claimed
US-20050180936-A1 Keratin fiber make-up composition with long-term stability L'OREAL S.A. (FR) 2005-08-18 US claimed
EP-1552806-A1 Long lasting make-up composition for keratin fibers L'OREAL (FR) 2005-07-13 EP claimed
EP-1534218-A1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES L'OREAL (FR) 2005-06-01 EP claimed
EP-1534219-A1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES L'OREAL (FR) 2005-06-01 EP claimed
CN-1602838-A Cosmetic composition comprising a dispersion of at least one wax in at least one volatile oil OREAL (FR) 2005-04-06 CN claimed
EP-1516611-A1 Cosmetic composition comprising dispersions of waxes in volatile oils L'OREAL (FR) 2005-03-23 EP claimed
EP-1504745-A1 Make-up composition enabling the make-up of keratinous material, particularly keratinous fibers, like eyelashes L'OREAL (FR) 2005-02-09 EP claimed
WO-2004022009-A9 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES OREAL (FR) 2004-05-06 WO claimed
WO-2004022010-A1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES L'OREAL (FR) 2004-03-18 WO claimed
WO-2004022009-A1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES L'OREAL (FR) 2004-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius CUTA, IL33, LSS LMNA 742/4885MAPT 2844/4885MAPK1 3433/4885
US-20050180936-A1 Keratin fiber make-up composition with long-term stability KRT18, DSG1, DSP LMNA 607/4885MAPT 21/4885MAPK1 927/4885
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS DSG1, AQP3, AQP1 LMNA 1013/4885MAPT 3896/4885MAPK1 4208/4885
US-10576031-B1 Exfoliating and hydrating makeup removing compositions DSG1, AQP3, AQP1 LMNA 1013/4885MAPT 3896/4885MAPK1 4208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.